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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Grik4
glutamate receptor, ionotropic, kainate 4
MGI:95817
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Epha4tm2Kldr/Epha4tm2.1Kldr
Grik4tm1.1(cre)Slab/Grik4+
involves: C57BL/6 		normal nervous system phenotype J:154648
Grik4tm1(cre)Mim/Grik4+
Grin1tm1Mim/Grin1tm1Mim
involves: C57BL/6N 		abnormal brain wave pattern J:144994
abnormal nervous system electrophysiology J:144994
abnormal postural reflex J:144994
increased susceptibility to pharmacologically induced seizures J:144994
normal nervous system phenotype J:144994
tonic-clonic seizures J:144994
Grik4tm1.1Sfh/Grik4tm1.1Sfh
Grik5tm1Cont/Grik5tm1Cont
involves: 129S/SvEv * 129S4/SvJae 		abnormal excitatory postsynaptic currents J:155003
decreased paired-pulse facilitation J:155003
decreased physiological sensitivity to xenobiotic J:155003
Grin2btm1Ksak/Grin2btm1Ksak
Grik4tm1(cre)Ksak/Grik4+
C57BL/6-Grin2btm1Ksak Grik4tm1(cre)Ksak 		abnormal dendrite morphology J:152455
abnormal synapse morphology J:152455
absence of NMDA-mediated synaptic currents J:152455
normal nervous system phenotype J:152455
reduced long-term potentiation J:152455
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory