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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
MGI:95809
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Adarb1tm1.1Skwa/Adarb1tm1.1Skwa
Gria2tm1.1Phs/Gria2tm1.1Phs
Tg(SLC18A3-cre)KMisa/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
normal behavior/neurological phenotype J:164294
normal nervous system phenotype J:164294
Adarb1tm1Phs/Adarb1tm1Phs
Gria2tm1.1Phs/Gria2+
involves: 129S1/Sv * 129X1/SvJ
postnatal lethality, incomplete penetrance J:63273
Adarb1tm1Phs/Adarb1tm1Phs
Gria2tm1.1Phs/Gria2tm1.1Phs
involves: 129S1/Sv * 129X1/SvJ
no abnormal phenotype detected J:63273
Gria2tm1Rod/Gria2+
Tg(SOD1*G93A)1Gur/0
B6.Cg-Gria2tm1Rod Tg(SOD1*G93A)1Gur
decreased motor neuron number J:104951
Gria2tm1Rod/Gria2tm1Rod
Gria3tm1Zpj/Y
involves: 129/Sv * C57BL/6
abnormal excitatory postsynaptic potential J:84336
abnormal long-term depression J:84336
abnormal motor capabilities/coordination/movement J:84336
abnormal synaptic plasticity J:84336
decreased body size J:84336
decreased locomotor activity J:84336
enhanced long-term potentiation J:84336
normal nervous system phenotype J:84336
postnatal lethality, incomplete penetrance J:84336
tremors J:84336
Gria2tm1Rod/Gria2tm1Rod
Tg(SOD1*G93A)1Gur/0
B6.Cg-Gria2tm1Rod Tg(SOD1*G93A)1Gur
abnormal AMPA-mediated synaptic currents J:104951
decreased grip strength J:104951
decreased motor neuron number J:104951
hindlimb paralysis J:104951
impaired coordination J:104951
premature death J:104951
Tg(Gria2*586N)238.2Rsp/0
Tg(SOD1*G93A)1Gur/0
involves: C57BL/6Ico
impaired righting response J:97818
premature death J:97818
tremors J:97818
weight loss J:97818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory