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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gnai2
G protein subunit alpha i2
MGI:95772
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gnai1tm1Drs/Gnai1tm1Drs
Gnai2tm1Lbi/Gnai2tm1Lbi
involves: 129S7/SvEvBrd 		abnormal sternocostal joint morphology J:193170
normal skeleton phenotype J:193170
Gnai2tm1Lbi/Gnai2+
Tg(WTbeta2)4Wjk/0
B6.Cg-Gnai2tm1Lbi Tg(WTbeta2)4Wjk 		abnormal liver morphology J:125581
ascites J:125581
cyanosis J:125581
dilated heart J:125581
fatigue J:125581
increased heart weight J:125581
premature death J:125581
pulmonary edema J:125581
respiratory distress J:125581
Gnai2tm1Lbi/Gnai2+
Gnai3tm1Lbi/Gnai3tm1Lbi
involves: 129S/SvEv * 129S7/SvEvBrd 		abnormal sternocostal joint morphology J:193170
rib fusion J:193170
Gnai2tm1Lbi/Gnai2tm1Lbi
Tg(WTbeta2)4Wjk/0
B6.Cg-Gnai2tm1Lbi Tg(WTbeta2)4Wjk 		decreased birth body size J:125581
dilated heart J:125581
embryonic lethality, incomplete penetrance J:125581
postnatal lethality, complete penetrance J:125581
weakness J:125581
Gnai2tm2.1Lbi/Gnai2+
Gnai3tm1Lbi/Gnai3tm1Lbi
Sox9tm3(cre)Crm/Sox9+
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 		rib fusion J:193170
Gnai2tm2.1Lbi/Gnai2tm2.1Lbi
Gnai3tm1Lbi/Gnai3tm1Lbi
Sox9tm3(cre)Crm/Sox9+
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 		lumbar vertebral fusion J:193170
rib fusion J:193170
Gnai2tm2.1Lbi/Gnai2tm2.1Lbi
Gnai3tm1Lbi/Gnai3tm1Lbi
Tg(Myog-cre)1Eno/0
involves: 129S/SvEv * C57BL/6 		rib fusion J:193170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory