About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gna13
guanine nucleotide binding protein, alpha 13
MGI:95768
27 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6N
abnormal B cell physiology J:117663
decreased marginal zone B cell number J:117663
Gna12tm1.1Cgh/Gna12tm1.1Cgh
Gna13tm2Cgh/Gna13tm2Cgh
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA
abnormal germinal center B cell morphology J:174313
decreased B cell apoptosis J:174313
increased germinal center B cell number J:174313
Gna12tm1Citb/Gna12+
Gna13tm1Soff/Gna13+
involves: 129S1/Sv * C57BL/6
no abnormal phenotype detected J:77728
Gna12tm1Citb/Gna12+
Gna13tm1Soff/Gna13tm1Soff
involves: 129S1/Sv * C57BL/6
embryonic growth arrest J:77728
embryonic lethality, complete penetrance J:77728
Gna12tm1Citb/Gna12tm1Citb
Gna13tm1Soff/Gna13+
involves: 129S1/Sv * C57BL/6
embryonic lethality, complete penetrance J:77728
Gna12tm1Citb/Gna12tm1Citb
Gna13tm1Soff/Gna13tm1Soff
involves: 129S1/Sv * C57BL/6
embryonic growth arrest J:77728
embryonic lethality, complete penetrance J:77728
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff
Tg(Lck-cre)548Jxm/0
involves: 129S1/Sv * C57BL/6 * CBA
abnormal CD4-positive, alpha-beta T cell physiology J:149560
increased CD4-positive, alpha beta T cell number J:149560
increased CD8-positive, alpha-beta T cell number J:149560
increased interleukin-2 secretion J:149560
increased susceptibility to autoimmune diabetes J:149560
increased susceptibility to type IV hypersensitivity reaction J:149560
increased T cell proliferation J:149560
lymph node hyperplasia J:149560
thymus hyperplasia J:149560
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA * FVB/N
abnormal blood coagulation J:99597
abnormal platelet physiology J:99597
decreased platelet aggregation J:99597
increased bleeding time J:99597
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff
X/Tg(Myh11-cre/ERT2)1Soff
involves: 129S1/Sv * FVB/N
decreased systemic arterial blood pressure J:141641
decreased vasoconstriction J:141641
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2.1Soff/Gna13tm2.1Soff
Tg(Tek-cre/ERT2)1Soff/?
involves: 129P2/OlaHsd * 129S1/Sv * FVB/N
normal cardiovascular system phenotype J:146132
Gna12tm1Citb/Gna12tm1Citb
Gna13tm2Cgh/Gna13tm2Cgh
Grhl3tm1(cre)Cgh/Grhl3+
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae * C57BL/6 * SJL
abnormal embryo development J:157446
abnormal embryo turning J:157446
embryonic lethality during organogenesis, complete penetrance J:157446

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/13/2019
MGI 6.14
The Jackson Laboratory