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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gjc1
gap junction protein, gamma 1
MGI:95718
40 phenotypes from 9 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gjc1tm1.1(Gjd2)Kwi/Gjc1tm1.1(Gjd2)Kwi
Tg(Myh6-cre)2182Mds/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL 		abnormal atrioventricular cushion morphology J:182927
abnormal impulse conducting system conduction J:182927
atrioventricular block J:182927
congestive heart failure J:182927
decreased cardiac muscle contractility J:182927
decreased embryo size J:182927
decreased heart rate J:182927
dilated heart J:182927
embryonic growth retardation J:182927
embryonic lethality during organogenesis, complete penetrance J:182927
enlarged heart J:182927
pericardial effusion J:182927
Gjc1tm1.1(Gjd2)Kwi/Gjc1tm1.1(Gjd2)Kwi
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * SJL 		normal nervous system phenotype J:182927
normal vision/eye phenotype J:182927
Gjc1tm1.1(KOMP)Vlcg/Gjc1tm1.1(KOMP)Vlcg
C57BL/6N-Gjc1tm1.1(KOMP)Vlcg/MbpMmucd 		preweaning lethality, complete penetrance J:211773
Gjc1tm1.1(KOMP)Vlcg/Gjc1tm1.1(KOMP)Vlcg
C57BL/6N-Gjc1tm1.1(KOMP)Vlcg/Ucd 		abnormal embryo size J:211773
abnormal pericardium morphology J:211773
edema J:211773
embryonic lethality prior to tooth bud stage J:211773
Gjc1tm1.1Kni/Gjc1tm1.1Kni
involves: 129S/SvEv * C57BL/6 		abnormal heart development J:63214
abnormal heart looping J:63214
absent atrioventricular cushions J:63214
absent trabeculae carneae J:63214
decreased cardiac muscle contractility J:63214
decreased embryo size J:63214
embryonic growth arrest J:63214
embryonic lethality during organogenesis, complete penetrance J:63214
enlarged heart J:63214
heart block J:63214
increased apoptosis J:63214
small placenta J:63214
Gjc1tm1Kni/Gjc1tm1Kni
involves: 129S/SvEv * C57BL/6 		abnormal heart development J:63214
abnormal heart looping J:63214
absent atrioventricular cushions J:63214
absent trabeculae carneae J:63214
decreased cardiac muscle contractility J:63214
decreased embryo size J:63214
embryonic growth arrest J:63214
embryonic lethality during organogenesis, complete penetrance J:63214
enlarged heart J:63214
heart block J:63214
increased apoptosis J:63214
small placenta J:63214
Gjc1tm1Kwi/Gjc1tm1Kwi
Tg(Myh6-icre/ERT2)#Wet/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal heart electrocardiography waveform feature J:205110
abnormal sinoatrial node conduction J:205110
normal cardiovascular system phenotype J:205110
embryonic lethality during organogenesis, complete penetrance J:205110
prolonged PQ interval J:205110
Gjc1tm1Kwi/Gjc1tm1Weil
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal eye electrophysiology J:95984
Gjc1tm1Weil/Gjc1tm1Weil
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal eye electrophysiology J:95984
abnormal eye physiology J:95984
Gjc1tm2.1Kni/Gjc1tm2.1Kni
Not Specified 		decreased cardiac output J:103078
impaired hematopoiesis J:103078
increased embryonic neuroepithelium apoptosis J:103078
thin myocardium J:103078
Gjc1tm2Kni/Gjc1tm2Kni
Tg(ACTC1-cre)1Miwa/0
involves: C57BL/6 * DBA 		abnormal impulse conducting system conduction J:103078
abnormal placenta vasculature J:103078
decreased cardiac output J:103078
embryonic lethality during organogenesis, complete penetrance J:103078
impaired hematopoiesis J:103078
increased embryonic neuroepithelium apoptosis J:103078
thin myocardium J:103078
Tg(Myh6-Gja7)927Kaya/0
involves: C57BL/6J * SJL/J 		abnormal myocardial fiber physiology J:104791
irregular heartbeat J:104791
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory