Gbx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gbx1
gastrulation brain homeobox 1
MGI:95667

22 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gbx1^tm1.1Stwt/Gbx1^tm1.1Stwt involves: C57BL/6 * FVB/N	abnormal gait	J:197199
	abnormal locomotor behavior	J:197199
	abnormal proprioceptive neuron morphology	J:197199
	decreased motor neuron number	J:197199
	normal nervous system phenotype	J:197199
Gbx1^{tm1b(KOMP)Wtsi}/Gbx1^{tm1b(KOMP)Wtsi} C57BL/6N-Gbx1^{tm1b(KOMP)Wtsi}/H	abnormal behavior	J:211773
	abnormal gait	J:211773
	abnormal optic disk morphology	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	enlarged urinary bladder	J:211773
	increased anxiety-related response	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased thigmotaxis	J:211773
	limb grasping	J:211773
Gbx1^tm1Mrh/Gbx1^tm1Mrh involves: 129P2/OlaHsd * C57BL/6J	abnormal GABAergic neuron morphology	J:201154
	abnormal gait	J:201154
	abnormal locomotor activation	J:201154
	decreased locomotor activity	J:201154
	impaired coordination	J:201154
	increased anxiety-related response	J:201154
	increased nerve conduction velocity	J:201154
	increased thermal nociceptive threshold	J:201154
Gbx1^tm1Stwt/Gbx1^tm1Stwt involves: C57BL/6	no abnormal phenotype detected	J:197199

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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