111 phenotypes from 19 alleles in 19 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gba1em1(IMPC)H/Gba1+ C57BL/6N-Gba1em1(IMPC)H/H	increased circulating amylase level	J:211773
	increased mean platelet volume	J:211773
	prolonged QRS complex duration	J:211773
Gba1em1(IMPC)H/Gba1em1(IMPC)H C57BL/6N-Gba1em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Gba1tm1.1Clk/Gba1tm1.1Clk involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	aphagia	J:117763
	neonatal lethality, complete penetrance	J:117763
	reddish skin	J:117763
	wrinkled skin	J:117763
Gba1tm1.1Eginn/Gba1tm1.1Eginn involves: 129X1/SvJ * C57BL/6	abnormal enzyme/coenzyme activity	J:211953
	abnormal striatum morphology	J:211953
	alpha-synuclein inclusion body	J:211953
	astrocytosis	J:211953
Gba1tm1.1Karl/Gba1+ involves: 129S1/Sv * 129X1/SvJ	abnormal enzyme/coenzyme activity	J:113751
Gba1tm1.1Karl/Gba1tm1.1Karl involves: 129S1/Sv * 129X1/SvJ	neonatal lethality, complete penetrance	J:113751
Gba1tm1.1Mjff/Gba1+ C57BL/6NTac-Gba1tm1.1Mjff	no abnormal phenotype detected	J:101977
Gba1tm1.1Pmis/Gba1tm1.1Pmis Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal circulating chemokine level	J:167081
	abnormal circulating cytokine level	J:167081
	abnormal osteoblast differentiation	J:167081
	abnormal skeleton physiology	J:167081
	abnormal T cell differentiation	J:167081
	abnormal thymus morphology	J:167081
	abnormal trabecular bone morphology	J:167081
	decreased body size	J:167081
	decreased bone mineral density	J:167081
	decreased bone ossification	J:167081
	decreased circulating HDL cholesterol level	J:167081
	decreased circulating interleukin-1 alpha level	J:167081
	decreased circulating interleukin-1 beta level	J:167081
	decreased circulating interleukin-6 level	J:167081
	decreased circulating tumor necrosis factor level	J:167081
	decreased double-positive T cell number	J:167081
	decreased hemoglobin content	J:167081
	enlarged liver	J:167081
	enlarged spleen	J:167081
	extramedullary hematopoiesis	J:167081
	increased circulating aspartate transaminase level	J:167081
	increased circulating interferon-gamma level	J:167081
	increased circulating interleukin-2 level	J:167081
	increased circulating interleukin-3 level	J:167081
	increased circulating interleukin-9 level	J:167081
	increased circulating interleukin-10 level	J:167081
	increased circulating interleukin-13 level	J:167081
	increased liver weight	J:167081
	kyphosis	J:167081
	pallor	J:167081
	spleen hyperplasia	J:167081
Gba1tm1.1Pmis/Gba1tm1.2Pmis Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal circulating chemokine level	J:167081
	abnormal circulating cytokine level	J:167081
	abnormal osteoblast differentiation	J:167081
	abnormal skeleton physiology	J:167081
	abnormal T cell differentiation	J:167081
	abnormal thymus morphology	J:167081
	abnormal trabecular bone morphology	J:167081
	decreased body size	J:167081
	decreased bone mineral density	J:167081
	decreased bone ossification	J:167081
	decreased circulating HDL cholesterol level	J:167081
	decreased circulating interleukin-1 alpha level	J:167081
	decreased circulating interleukin-1 beta level	J:167081
	decreased circulating interleukin-6 level	J:167081
	decreased circulating tumor necrosis factor level	J:167081
	decreased double-positive T cell number	J:167081
	decreased hemoglobin content	J:167081
	enlarged liver	J:167081
	enlarged spleen	J:167081
	extramedullary hematopoiesis	J:167081
	increased circulating aspartate transaminase level	J:167081
	increased circulating interferon-gamma level	J:167081
	increased circulating interleukin-2 level	J:167081
	increased circulating interleukin-3 level	J:167081
	increased circulating interleukin-9 level	J:167081
	increased circulating interleukin-10 level	J:167081
	increased circulating interleukin-13 level	J:167081
	increased liver weight	J:167081
	kyphosis	J:167081
	pallor	J:167081
	spleen hyperplasia	J:167081
Gba1tm1.1Smoc/Gba1tm1.1Smoc involves: C57BL/6J	abnormal epidermis stratum corneum morphology	J:325557
	abnormal epidermis stratum granulosum morphology	J:325557
	abnormal epidermis stratum spinosum morphology	J:325557
	abnormal skin turgor	J:325557
	decreased body size	J:325557
	postnatal lethality, complete penetrance	J:325557
	reddish skin	J:325557
	wrinkled skin	J:325557
Gba1tm1Clk/Gba1tm1.1Clk Lyz2tm1(cre)Ifo/Lyz2+ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal enzyme/coenzyme activity	J:117763
Gba1tm1Clk/Gba1tm1.1Clk Tg(EIIa-cre)C5379Lmgd/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal enzyme/coenzyme activity	J:117763
Gba1tm1Clk/Gba1tm1.1Clk Tg(Tek-cre)12Flv/0 involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J	abnormal bone marrow morphology	J:117763
	abnormal enzyme/coenzyme activity	J:117763
	abnormal liver morphology	J:117763
	abnormal macrophage morphology	J:117763
	abnormal spleen morphology	J:117763
	increased spleen weight	J:117763
Gba1tm1Ggb/Gba1tm1Ggb involves: 129S5/SvEvBrd * C57BL/6	abnormal skin condition	J:86334
	dry skin	J:86334
	perinatal lethality, complete penetrance	J:86334
	wrinkled skin	J:86334
Gba1tm1Karl/Gba1tm1.1Karl Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal bone marrow morphology	J:113751
	abnormal enzyme/coenzyme activity	J:113751
	abnormal immune system organ morphology	J:113751
	abnormal response to transplant	J:113751
	abnormal spleen morphology	J:113751
	decreased hematocrit	J:113751
	decreased hemoglobin content	J:113751
	decreased mean corpuscular volume	J:113751
	enlarged liver	J:113751
	enlarged spleen	J:113751
	intermingled spleen red and white pulp	J:113751
	pale liver	J:113751
Gba1tm1Karl/Gba1tm1Karl Tg(Nes-cre)1Kln/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal brain morphology	J:127108
	abnormal gait	J:127108
	abnormal lipid homeostasis	J:127108
	abnormal microglial cell morphology	J:127108
	astrocytosis	J:127108
	neuron degeneration	J:127108
	paralysis	J:127108
	premature death	J:127108
	seizures	J:127108
Gba1tm1Nsb/Gba1tm1Nsb involves: 129S/SvEv * C57BL/6	abnormal food intake	J:1100
	abnormal macrophage morphology	J:1100
	abnormal respiration	J:1100
	akinesia	J:1100
	cyanosis	J:1100
	decreased birth weight	J:1100
	perinatal lethality	J:1100
Gba1tm1Rlp/Gba1tm1Rlp involves: 129S4/SvJae	hyperkeratosis	J:46243
	postnatal lethality, complete penetrance	J:46243
	reddish skin	J:46243
	wrinkled skin	J:46243
Gba1tm1Rlp/Gba1tm1Rlp involves: 129S4/SvJae * C57BL/6	abnormal enzyme/coenzyme activity	J:76409
	abnormal inflammatory response	J:76409
	abnormal Kupffer cell morphology	J:76409
	abnormal lymph node morphology	J:76409
	abnormal macrophage morphology	J:76409
	abnormal spleen physiology	J:76409
	anemia	J:76409
	decreased body weight	J:76409
	decreased circulating cholesterol level	J:76409
	decreased erythrocyte cell number	J:76409
	decreased hematocrit	J:76409
	decreased hemoglobin content	J:76409
	decreased leukocyte cell number	J:76409
	decreased survivor rate	J:76409
	enlarged liver	J:76409
	hyperkeratosis	J:76409
	increased circulating alanine transaminase level	J:76409
	increased circulating aspartate transaminase level	J:76409
	increased hepatocyte apoptosis	J:76409
	increased IgG level	J:76409
	increased liver weight	J:76409
	increased spleen weight	J:76409
	lipofuscinosis	J:76409
	liver inflammation	J:76409
	lung inflammation	J:76409
	lymph node inflammation	J:76409
	postnatal lethality, incomplete penetrance	J:76409
	normal skeleton phenotype	J:76409
	skin inflammation	J:76409
	thick epidermis	J:76409
Gba1tm2.1Eginn/Gba1tm2.1Eginn involves: 129X1/SvJ * C57BL/6	abnormal enzyme/coenzyme activity	J:211953
	abnormal striatum morphology	J:211953
	alpha-synuclein inclusion body	J:211953
	astrocytosis	J:211953
Gba1tm2Ggb/Gba1tm1Nsb involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6	abnormal liver physiology	J:86334
	abnormal pulmonary circulation	J:86334
	abnormal spleen morphology	J:86334
Gba1tm2Ggb/Gba1tm2Ggb involves: 129S5/SvEvBrd * C57BL/6	abnormal liver physiology	J:86334
	abnormal pulmonary circulation	J:86334
	abnormal spleen morphology	J:86334
Gba1tm2Karl/Gba1tm2Karl involves: 129S1/Sv * 129X1/SvJ	abnormal skin condition	J:127108
	neonatal lethality, complete penetrance	J:127108
Gba1tm2Karl/Gba1tm2Karl Tg(KRT14-cre)8Brn/? involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal brain morphology	J:127108
	abnormal gait	J:127108
	abnormal lipid homeostasis	J:127108
	abnormal macrophage morphology	J:127108
	abnormal neuron morphology	J:127108
	decreased brain size	J:127108
	decreased cerebral cortex pyramidal cell number	J:127108
	decreased Purkinje cell number	J:127108
	hippocampal neuron degeneration	J:127108
	paralysis	J:127108
	postnatal lethality	J:127108
	seizures	J:127108
Gba1tm2Rlp/Gba1tm2Rlp involves: 129S4/SvJae	absent gastric milk in neonates	J:46243
	decreased birth body size	J:46243
	decreased skin turgor	J:46243
	dehydration	J:46243
	hyperkeratosis	J:46243
	postnatal lethality, complete penetrance	J:46243
	reddish skin	J:46243
	wrinkled skin	J:46243
Gba1tm3Ggb/Gba1tm1Nsb involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6	abnormal liver physiology	J:86334
	abnormal pulmonary circulation	J:86334
	abnormal spleen morphology	J:86334
Gba1tm3Ggb/Gba1tm3Ggb involves: 129S5/SvEvBrd	abnormal brain morphology	J:174780
	abnormal liver physiology	J:86334
	abnormal pulmonary circulation	J:86334
	abnormal spleen morphology	J:86334
Gba1tm4Ggb/Gba1tm1Nsb involves: 129S/SvEv * 129S5/SvEvBrd * C57BL/6	abnormal liver physiology	J:86334
	abnormal pulmonary circulation	J:86334
	abnormal spleen morphology	J:86334
Gba1tm4Ggb/Gba1tm4Ggb involves: 129S5/SvEvBrd * C57BL/6	abnormal liver physiology	J:86334
	abnormal pulmonary circulation	J:86334
	abnormal spleen morphology	J:86334