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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fn1
fibronectin 1
MGI:95566
72 phenotypes from 13 alleles in 13 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Fn1Gt(Ex180)Byg/Fn1Gt(Ex180)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal gastrulation J:70273
embryonic lethality, complete penetrance J:70273
Fn1tm1.1Sakai/Fn1tm1.1Sakai
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA
abnormal liver physiology J:214945
abnormal response to injury J:214945
Fn1tm1Bwg/Fn1tm1Bwg
involves: 129S4/SvJae * BALB/c * C57BL/6J
normal cardiovascular system phenotype J:93027
normal neoplasm J:93027
Fn1tm1Bwg/Fn1tm1Bwg
involves: 129S4/SvJae * C57BL/6
normal immune system phenotype J:90917
no abnormal phenotype detected J:90917
Fn1tm1Feb/Fn1tm1Feb
involves: 129X1/SvJ
abnormal protein level J:84274
normal homeostasis/metabolism phenotype J:84274
premature death J:84274
normal reproductive system phenotype J:84274
Fn1tm1Hyn/Fn1tm1Hyn
involves: 129S2/SvPas * C57BL/6J
abnormal amnion morphology J:16247
abnormal cardiac jelly morphology J:16247
abnormal developmental patterning J:16247
abnormal dorsal aorta morphology J:16247
abnormal embryonic neuroepithelium morphology J:16247
abnormal embryonic tissue morphology J:16247
abnormal endocardium morphology J:16247
abnormal extraembryonic tissue morphology J:16247
abnormal heart development J:16247
abnormal lateral plate mesoderm morphology J:16247
abnormal mesoderm development J:16247
abnormal neural tube morphology J:16247
abnormal vasculogenesis J:16247
abnormal visceral yolk sac morphology J:16247
absent notochord J:16247
absent somites J:16247
absent visceral yolk sac blood islands J:16247
absent vitelline blood vessels J:16247
decreased embryo size J:16247
embryonic growth retardation J:16247
embryonic lethality during organogenesis, complete penetrance J:16247
failure of chorioallantoic fusion J:16247
failure of initiation of embryo turning J:16247
kinked neural tube J:16247
short rostral-caudal axis J:16247
thick myocardium J:16247
Fn1tm1Ksek/Fn1tm1Ksek
involves: 129P2/OlaHsd * 129/Sv
abnormal extracellular matrix morphology J:93250
normal cardiovascular system phenotype J:93027
decreased fibroblast proliferation J:93250
normal neoplasm J:93027
Fn1tm1Ref/Fn1tm1Ref
involves: 129S1/Sv * 129X1/SvJ
no abnormal phenotype detected J:67961
Fn1tm1Ref/Fn1tm1Ref
Tg(Col2a1-cre)1Asz/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
normal skeleton phenotype J:85994
Fn1tm1Ref/Fn1tm1Ref
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal thrombosis J:82373
normal homeostasis/metabolism phenotype J:67961
increased cerebral infarction size J:67961
increased neuron apoptosis J:67961
increased susceptibility to ischemic brain injury J:67961
Fn1tm2.1Ref/Fn1tm2.1Ref
involves: 129S1/Sv * 129X1/SvJ
abnormal embryonic tissue morphology J:177821
abnormal rostral-caudal patterning of the somites J:177821
abnormal vitelline vasculature morphology J:177821
absent limb buds J:177821
normal cardiovascular system phenotype J:177821
normal craniofacial phenotype J:177821
embryonic lethality during organogenesis, complete penetrance J:177821
incomplete embryo turning J:177821
incomplete somite formation J:177821
increased tail bud apoptosis J:177821
kinked neural tube J:177821
kinked tail J:177821
short rostral-caudal axis J:177821
Fn1tm2Bwg/Fn1tm2Bwg
involves: 129S4/SvJae
no abnormal phenotype detected J:90917
Fn1tm2Feb/Fn1tm2Feb
involves: 129X1/SvJ
impaired wound healing J:84274
premature death J:84274
skin lesions J:84274
spontaneous skin ulceration J:84274
Fn1tm2Hyn/Fn1tm2Hyn
involves: 129S2/SvPas * C57BL/6J
abnormal amnion morphology J:36210
abnormal heart morphology J:36210
abnormal notochord morphology J:36210
abnormal visceral yolk sac morphology J:36210
absent somites J:36210
absent vitelline blood vessels J:36210
embryonic growth retardation J:36210
embryonic lethality during organogenesis, complete penetrance J:36210
head mesenchyme hypoplasia J:36210
kinked neural tube J:36210
short rostral-caudal axis J:36210
Fn1tm3Hyn/Fn1tm3Hyn
involves: 129S2/SvPas * C57BL/6J
abnormal amnion morphology J:36210
abnormal heart morphology J:36210
abnormal notochord morphology J:36210
abnormal visceral yolk sac morphology J:36210
absent somites J:36210
absent vitelline blood vessels J:36210
embryonic growth retardation J:36210
embryonic lethality during organogenesis, complete penetrance J:36210
head mesenchyme hypoplasia J:36210
kinked neural tube J:36210
short rostral-caudal axis J:36210
Fn1tm4Hyn/Fn1tm4Hyn
129S4.129P2-Fn1tm4Hyn
prenatal lethality, complete penetrance J:126737
Fn1tm4Hyn/Fn1tm4Hyn
B6.129P2-Fn1tm4Hyn
prenatal lethality, incomplete penetrance J:126737
Fn1tm4Hyn/Fn1tm4Hyn
involves: 129P2/OlaHsd * C57BL/6J
abnormal atrioventricular cushion morphology J:126737
abnormal cardiac outflow tract development J:126737
abnormal placenta vasculature J:126737
abnormal vascular development J:126737
abnormal vascular smooth muscle morphology J:126737
abnormal visceral yolk sac morphology J:126737
abnormal vitelline vascular remodeling J:126737
absent vitelline blood vessels J:126737
anemia J:126737
disorganized yolk sac vascular plexus J:126737
distended pericardium J:126737
embryonic lethality during organogenesis, incomplete penetrance J:126737
hemorrhage J:126737
kinked neural tube J:126737

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/16/2019
MGI 6.13
The Jackson Laboratory