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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fkbp1a
FK506 binding protein 1a
MGI:95541
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cdh5tm4(Cdh5/Fkbp,Ptprb/Mtor*)Dvst/Cdh5tm4(Cdh5/Fkbp,Ptprb/Mtor*)Dvst
involves: C57BL/6
abnormal cellular extravasation J:178759
decreased vascular permeability J:178759
impaired neutrophil recruitment J:178759
Tg(Csf1r-EGFP-NGFR/FKBP1A/TNFRSF6)2Bck/Tg(Csf1r-EGFP-NGFR/FKBP1A/TNFRSF6)2Bck
C57BL/6-Tg(Csf1r-EGFP-NGFR/FKBP1A/TNFRSF6)2Bck
no abnormal phenotype detected J:89035
Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0
involves: FVB/N
increased prostate gland adenocarcinoma incidence J:184212, J:206727
prostate gland hyperplasia J:184212, J:206727
Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps/0
Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0
involves: FVB/N
increased prostate gland adenocarcinoma incidence J:206727
increased spindle cell carcinoma incidence J:206727
Tg(Myh6-FKBP1A)4Shou/0
involves: C3HeB/FeJ * DBA/2J
abnormal heart electrocardiography waveform feature J:183588
abnormal impulse conducting system conduction J:183588
abnormal myocardial fiber physiology J:183588
atrioventricular block J:183588
decreased heart rate J:183588
enlarged heart left atrium J:183588
enlarged heart right atrium J:183588
irregular heartbeat J:183588
lethality, incomplete penetrance J:183588
prolonged P wave J:183588
prolonged PQ interval J:183588
prolonged QRS complex duration J:183588
Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0
FVB-Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp
increased metastatic potential J:130340
increased prostate gland adenocarcinoma incidence J:130340
increased prostate gland tumor incidence J:130340
increased prostate intraepithelial neoplasia incidence J:87092, J:130340
increased sarcoma incidence J:130340
prostate gland cysts J:130340
prostate gland hyperplasia J:87092
Tg(Pbsn-Fgfr1/Fkbp1a)#aDmsp/0
Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps/0
involves: FVB/N
increased prostate gland adenocarcinoma incidence J:206727
Tg(Pbsn-Lrp5/Fkbp1a,-luc*)#Dmps/0
involves: FVB/N
prostate gland hyperplasia J:206727

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/13/2018
MGI 6.11
The Jackson Laboratory