About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fgfr1
fibroblast growth factor receptor 1
MGI:95522
264 phenotypes from 36 alleles in 39 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
En1tm2(cre)Wrst/En1+
Fgfr1tm1Jpa/Fgfr1tm1Jpa
involves: 129S1/Sv * 129X1/SvJ
abnormal cerebellum morphology J:83004
abnormal gait J:83004
abnormal locus ceruleus morphology J:83004
abnormal midbrain morphology J:83004
abnormal posture J:83004
abnormal trochlear nerve morphology J:83004
absent cerebellum vermis J:83004
absent inferior colliculus J:83004
impaired coordination J:83004
Fgfr1Eask/Fgfr1+
BALB/cByJ-Fgfr1Eask/GrsrJ
abnormal ear position J:179274
abnormal ear shape J:179274
abnormal outer ear morphology J:179274
increased or absent threshold for auditory brainstem response J:179274
lowered ear position J:179274
normal vision/eye phenotype J:179274
Fgfr1Eask/Fgfr1Eask
BALB/cByJ-Fgfr1Eask/GrsrJ
prenatal lethality, complete penetrance J:179274
Fgfr1Hspy/Fgfr1+
(C3HeB/FeJ-Fgfr1Hspy x C57BL/6J)F1
abnormal outer ear morphology J:171915
abnormal stapes morphology J:171915
normal hearing/vestibular/ear phenotype J:171915
Fgfr1Hspy/Fgfr1+
C3HeB/FeJ-Fgfr1Hspy
abnormal incus morphology J:171915
abnormal outer ear morphology J:171915
abnormal snout morphology J:171915
abnormal stapes morphology J:171915
normal hearing/vestibular/ear phenotype J:171915
short snout J:171915
small ears J:171915
Fgfr1Hspy/Fgfr1+
C3HeB/FeJ-Hspy
abnormal auditory bulla morphology J:95895
abnormal cochlear nerve compound action potential J:95895
abnormal ear physiology J:95895
abnormal ear shape J:95895
abnormal incudostapedial joint morphology J:95895
abnormal incus body morphology J:95895
abnormal incus long process morphology J:95895
abnormal incus morphology J:95895
abnormal incus short process morphology J:95895
abnormal inner ear morphology J:95895
abnormal middle ear morphology J:95895
abnormal outer ear morphology J:95895
abnormal pinna reflex J:95895
abnormal stapes morphology J:95895
abnormal stapes posterior crus morphology J:95895
absent incus lenticular process J:95895
absent round window J:95895
absent stapes head J:95895
decreased cochlear outer hair cell number J:95895
decreased endocochlear potential J:95895
decreased round window size J:95895
excessive cerumen J:95895
increased susceptibility to otitis media J:95895
lowered ear position J:95895
short mandible J:95895
short nasal bone J:95895
small cranium J:95895
small ears J:95895
Fgfr1Hspy/Fgfr1Hspy
C3HeB/FeJ-Fgfr1Hspy
abnormal embryonic-extraembryonic boundary morphology J:171915
embryonic growth retardation J:171915
embryonic lethality between somite formation and embryo turning, complete penetrance J:171915
Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd
increased respiratory quotient J:211773
Fgfr1tm1.1(KOMP)Vlcg/Fgfr1tm1.1(KOMP)Vlcg
C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd
abnormal embryo size J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Fgfr1tm1.1Jpa/Fgfr1tm1.1Jpa
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * ICR
abnormal gastrulation J:83004
embryonic lethality, complete penetrance J:83004
Fgfr1tm1.1Upir/Fgfr1tm1.1Upir
involves: ICR
abnormal brain morphology J:78879
abnormal craniofacial morphology J:78879
abnormal developmental patterning J:78879
abnormal embryonic growth/weight/body size J:78879
abnormal embryonic tissue morphology J:78879
abnormal extraembryonic tissue morphology J:78879
abnormal heart development J:78879
abnormal neural tube morphology J:78879
embryonic lethality, complete penetrance J:78879
Fgfr1tm1Cxd/Fgfr1tm1Cxd
involves: 129S6/SvEvTac * NIH Black Swiss
abnormal axial skeleton morphology J:54222
abnormal developmental patterning J:54222
abnormal embryonic tissue morphology J:54222
abnormal neural tube morphology J:54222
embryonic lethality, complete penetrance J:54222
Fgfr1tm1Jpa/Fgfr1tm1.1Jpa
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
abnormal craniofacial bone morphology J:81179
cleft palate J:81179
normal craniofacial phenotype J:81179
Fgfr1tm1Jpa/Fgfr1tm1Jpa
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal cerebellum development J:83004
abnormal cerebellum vermis morphology J:83004
absent inferior colliculus J:83004
neonatal lethality J:83004
Fgfr1tm1Jpa/Fgfr1tm1Jpa
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
abnormal hyoid bone lesser horn morphology J:81179
cleft palate J:81179
normal craniofacial phenotype J:81179
Fgfr1tm1Jpa/Fgfr1tm1Jpa
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal medial nasal prominence morphology J:298139
abnormal palatal mesenchymal cell proliferation J:298139
abnormal palatal rugae morphology J:298139
abnormal secondary palate development J:298139
abnormal tongue position J:298139
abnormal tooth development J:298139
cleft primary palate J:298139
cleft secondary palate J:298139
cleft upper lip J:298139
complete cleft palate J:298139
decreased palatal shelf size J:298139
failure of palatal shelf elevation J:298139
micrognathia J:298139
palatal shelves fail to meet at midline J:298139
persistence of medial edge epithelium during palatal shelf fusion J:298139
Fgfr1tm1Jrt/Fgfr1tm1Jrt
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)
abnormal chorion morphology J:22117
abnormal egg cylinder morphology J:22117
abnormal extraembryonic tissue morphology J:22117
abnormal gastrulation movements J:22117
abnormal head fold morphology J:22117
abnormal head mesenchyme morphology J:22117
abnormal heart tube morphology J:22117
abnormal mesoderm development J:22117
abnormal midbrain morphology J:22117
abnormal neural fold morphology J:22117
abnormal neural plate morphology J:22117
abnormal notochordal process morphology J:22117
abnormal posterior primitive streak morphology J:22117
abnormal primitive streak morphology J:22117
abnormal rostral-caudal body axis extension J:22117
abnormal visceral yolk sac endoderm morphology J:22117
abnormal visceral yolk sac mesenchyme morphology J:22117
abnormal visceral yolk sac morphology J:22117
absent somites J:22117
absent visceral yolk sac blood islands J:22117
decreased embryo size J:22117
decreased paraxial mesoderm size J:22117
embryonic growth retardation J:22117
embryonic lethality between implantation and somite formation, incomplete penetrance J:22117
embryonic lethality between somite formation and embryo turning, incomplete penetrance J:22117
embryonic lethality during organogenesis, incomplete penetrance J:22117
enlarged allantois J:22117
excessive folding of visceral yolk sac J:22117
failure of primitive streak formation J:22117
increased axial mesoderm size J:22117
kinked neural tube J:22117
Fgfr1tm1Jrt/Fgfr1tm2Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal carpal bone morphology J:49154
abnormal craniofacial bone morphology J:49154
abnormal digit morphology J:49154
abnormal limb morphology J:49154
abnormal sternocostal joint morphology J:49154
abnormal tarsal bone morphology J:49154
caudal body truncation J:49154
cervical vertebral transformation J:49154
decreased caudal vertebrae number J:49154
lumbar vertebral transformation J:49154
neonatal lethality, complete penetrance J:49154
oligodactyly J:49154
prenatal lethality, incomplete penetrance J:49154
rib fusion J:49154
sacral vertebral transformation J:49154
short tibia J:49154
syndactyly J:49154
vertebral transformation J:49154
Fgfr1tm1Jrt/Fgfr1tm4Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal tail development J:49154
prenatal lethality, complete penetrance J:49154
Fgfr1tm1Jrt/Fgfr1tm6.1Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal vertebrae morphology J:49154
cervical vertebral transformation J:49154
lumbar vertebral transformation J:49154
rib fusion J:49154
sacral vertebral transformation J:49154
thoracic vertebral transformation J:49154
Fgfr1tm1Led/Fgfr1tm1Led
involves: 129S4/SvJae * NIH Black Swiss
abnormal developmental patterning J:22118
abnormal egg cylinder morphology J:22118
abnormal extraembryonic tissue morphology J:22118
abnormal mesoderm development J:22118
abnormal neural tube morphology J:22118
abnormal primitive streak morphology J:22118
abnormal rostral-caudal axis patterning J:22118
abnormal rostral-caudal body axis extension J:22118
absent limb buds J:22118
absent somites J:22118
decreased embryo size J:22118
embryonic growth retardation J:22118
embryonic lethality between implantation and somite formation, incomplete penetrance J:22118
embryonic lethality during organogenesis, complete penetrance J:22118
excessive folding of visceral yolk sac J:22118
small proamniotic cavity J:22118
small visceral yolk sac J:22118
Fgfr1tm1Swnr/Fgfr1tm1Swnr
involves: 129S7/SvEvBrd * C57BL/6
normal integument phenotype J:101854
Fgfr1tm1Upir/Fgfr1tm1.1Upir
involves: C57BL/6J
abnormal fetal cardiomyocyte proliferation J:95803
abnormal heart development J:95803
abnormal myocardial fiber morphology J:95803
dilated heart left ventricle J:95803
dilated heart right ventricle J:95803
heart hypoplasia J:95803
increased heart atrium size J:95803
thin myocardium J:95803
Fgfr1tm1Upir/Fgfr1tm1.1Upir
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * ICR
abnormal cochlea morphology J:78879
abnormal cochlear hair cell development J:78879
abnormal cochlear sensory epithelium morphology J:78879
abnormal organ of Corti morphology J:78879
abnormal orientation of inner hair cell stereociliary bundles J:78879
absent cochlear outer hair cells J:78879
absent organ of Corti supporting cells J:78879
decreased cochlear hair cell number J:78879
increased cochlear inner hair cell number J:78879
neonatal lethality, complete penetrance J:78879
Fgfr1tm1Upir/Fgfr1tm1Upir
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * ICR
abnormal cochlear sensory epithelium morphology J:78879
abnormal organ of Corti morphology J:78879
neonatal lethality, complete penetrance J:78879
Fgfr1tm1Upir/Fgfr1tm1Upir
Tg(GFAP-cre)25Mes/0
involves: FVB/N
abnormal astrocyte morphology J:110263
abnormal brain commissure morphology J:110263
abnormal corpus callosum morphology J:110263
abnormal hippocampal commissure morphology J:110263
abnormal neuronal migration J:110263
Fgfr1tm1Upir/Fgfr1tm1Upir
Tg(KRT5-cre)5132Jlj/0
involves: C57BL/6 * C57BL/6J * DBA/2J
no abnormal phenotype detected J:158802
Fgfr1tm1Upir/Fgfr1tm1Upir
Tg(Mnx1-GFP)1Slp/?
Tg(Nes-cre)1Kln/?
Not Specified
abnormal axon guidance J:122940
abnormal motor neuron morphology J:122940
Fgfr1tm1Upir/Fgfr1tm1Upir
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL
abnormal corpus callosum morphology J:110263
abnormal dorsal telencephalic commissure morphology J:110263
abnormal frontal lobe morphology J:110263
Fgfr1tm2.1Cxd/Fgfr1+
B6J.129S6(Cg)-Fgfr1tm2.1Cxd
abnormal maxillary-premaxillary suture morphology J:228708
abnormal palatine bone morphology J:228708
abnormal viscerocranium morphology J:228708
Fgfr1tm2.1Cxd/Fgfr1+
D2.129S6(Cg)-Fgfr1tm2.1Cxd
abnormal basisphenoid bone morphology J:228708
abnormal maxillary-premaxillary suture morphology J:228708
abnormal palatine bone morphology J:228708
abnormal viscerocranium morphology J:228708
midface hypoplasia J:228708
premature maxillary-premaxillary suture closure J:228708
Fgfr1tm2.1Cxd/Fgfr1+
involves: 129S6/SvEvTac * FVB/N
abnormal craniofacial bone morphology J:63959
facial asymmetry J:63959
increased osteoblast cell number J:63959
increased osteoblast proliferation J:63959
long incisors J:63959
midface hypoplasia J:63959
ocular hypertelorism J:63959
premature coronal suture closure J:63959
premature cranial suture closure J:63959
premature metopic suture closure J:63959
premature sagittal suture closure J:63959
Fgfr1tm2.1Cxd/Fgfr1tm2.1Cxd
involves: 129S6/SvEvTac * FVB/N
abnormal craniofacial bone morphology J:63959
craniofacial asymmetry J:63959
decreased body size J:63959
ocular hypertelorism J:63959
premature cranial suture closure J:63959
short tail J:63959
Fgfr1tm2.1Jrt/Fgfr1tm2.1Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
no abnormal phenotype detected J:49154
Fgfr1tm2Jrt/Fgfr1tm2Jrt
involves: 129S1/Sv * 129X1/SvJ
abnormal cerebellum vermis morphology J:83004
decreased inferior colliculus size J:83004
Fgfr1tm2Jrt/Fgfr1tm2Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal carpal bone morphology J:49154
abnormal cervical axis morphology J:49154
abnormal craniofacial bone morphology J:49154
abnormal digit morphology J:49154
abnormal limb morphology J:49154
abnormal phalanx morphology J:49154
abnormal rostral-caudal axis patterning J:49154
abnormal sternocostal joint morphology J:49154
abnormal tail development J:49154
abnormal tarsal bone morphology J:49154
caudal body truncation J:49154
cervical vertebral transformation J:49154
decreased caudal vertebrae number J:49154
increased rib number J:49154
lumbar vertebral transformation J:49154
neonatal lethality, complete penetrance J:49154
oligodactyly J:49154
rib fusion J:49154
sacral vertebral transformation J:49154
small second pharyngeal arch J:49154
syndactyly J:49154
thoracic vertebral transformation J:49154
vertebral transformation J:49154
Fgfr1tm2Jrt/Fgfr1tm2Jrt
involves: 129S1/Sv * 129X1/SvJ * ICR
abnormal alisphenoid bone morphology J:81179
abnormal cochlear sensory epithelium morphology J:78879
abnormal hyoid bone lesser horn morphology J:81179
abnormal incus morphology J:81179
abnormal malleus morphology J:81179
abnormal middle ear ossicle morphology J:81179
abnormal neural crest cell migration J:81179
abnormal neural crest cell morphology J:81179
abnormal organ of Corti morphology J:78879
abnormal pterygoid bone morphology J:81179
abnormal retrotympanic process morphology J:81179
abnormal second pharyngeal arch morphology J:81179
abnormal secondary palate development J:81179
abnormal styloid process morphology J:81179
abnormal tongue position J:81179
absent gonial bone J:81179
absent middle ear ossicles J:81179
absent tympanic ring J:81179
cleft palate J:81179
decreased cochlear outer hair cell number J:78879
decreased tympanic ring size J:81179
failure of palatal shelf elevation J:81179
neonatal lethality, complete penetrance J:78879, J:81179
small ears J:81179
small gonial bone J:81179
Fgfr1tm2Jrt/Fgfr1tm2Jrt
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * ICR
abnormal alisphenoid bone morphology J:81179
abnormal incus morphology J:81179
abnormal malleus morphology J:81179
abnormal middle ear ossicle morphology J:81179
abnormal pterygoid bone morphology J:81179
abnormal second pharyngeal arch morphology J:81179
abnormal temporal bone squamous part morphology J:81179
normal craniofacial phenotype J:81179
decreased tympanic ring size J:81179
small gonial bone J:81179
Fgfr1tm3.1Cxd/Fgfr1tm3.1Cxd
involves: 129S6/SvEvTac * Black Swiss
embryonic lethality, complete penetrance J:75137
Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S6/SvEvTac
abnormal embryonic autopod plate morphology J:101736
oligodactyly J:101736
Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd
Tg(T-cre)1Lwd/0
involves: 129S6/SvEvTac * C3H * C57BL/6
abnormal apical ectodermal ridge morphology J:101736
abnormal axial skeleton morphology J:101736
abnormal cartilage development J:101736
abnormal forelimb bud morphology J:101736
abnormal forelimb stylopod morphology J:101736
abnormal forelimb zeugopod morphology J:101736
abnormal hindlimb morphology J:101736
abnormal neural plate morphology J:101736
abnormal somite size J:101736
forelimb oligodactyly J:101736
neonatal lethality, complete penetrance J:101736
Fgfr1tm3.1Jrt/Fgfr1tm3.1Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal gastrulation J:49154
abnormal somite development J:49154
absent somites J:49154
decreased paraxial mesoderm size J:49154
embryonic lethality during organogenesis, incomplete penetrance J:49154
Fgfr1tm3.1Sor/Fgfr1tm3.1Sor
involves: 129S4/SvJaeSor * C57BL/6J
abnormal neural tube closure J:105920
embryonic growth retardation J:105920
lethality throughout fetal growth and development, complete penetrance J:105920
spina bifida J:105920
Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S6/SvEvTac
abnormal embryonic autopod plate morphology J:101736
oligodactyly J:101736
Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd
Tg(T-cre)1Lwd/0
involves: 129S6/SvEvTac * C3H * C57BL/6
abnormal apical ectodermal ridge morphology J:101736
abnormal axial skeleton morphology J:101736
abnormal cartilage development J:101736
abnormal forelimb bud morphology J:101736
abnormal forelimb stylopod morphology J:101736
abnormal forelimb zeugopod morphology J:101736
abnormal hindlimb morphology J:101736
abnormal neural plate morphology J:101736
abnormal somite size J:101736
forelimb oligodactyly J:101736
neonatal lethality, complete penetrance J:101736
Fgfr1tm3Cxd/Fgfr1tm3Cxd
involves: 129S6/SvEvTac * Black Swiss
embryonic lethality between implantation and somite formation, complete penetrance J:75137
Fgfr1tm3Jrt/Fgfr1tm3Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal gastrulation J:49154
abnormal somite development J:49154
absent somites J:49154
decreased paraxial mesoderm size J:49154
embryonic lethality during organogenesis, incomplete penetrance J:49154
Fgfr1tm3Sor/Fgfr1tm3Sor
involves: 129S4/SvJaeSor * C57BL/6J
embryonic lethality, complete penetrance J:105920
Fgfr1tm4.1Jrt/Fgfr1tm4.1Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
no abnormal phenotype detected J:49154
Fgfr1tm4.1Jrt/Fgfr1tm4.1Jrt
involves: 129S1/Sv * 129X1/SvJ * ICR
normal hearing/vestibular/ear phenotype J:78879
Fgfr1tm4.1Sor/Fgfr1tm4.1Sor
involves: 129S4/SvJaeSor * C57BL/6J
abnormal digit morphology J:105920
decreased embryo size J:105920
lethality throughout fetal growth and development, incomplete penetrance J:105920
Fgfr1tm4Jrt/Fgfr1tm4Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal carpal bone morphology J:49154
abnormal cartilage development J:49154
abnormal cervical axis morphology J:49154
abnormal craniofacial bone morphology J:49154
abnormal forelimb morphology J:49154
abnormal limb morphology J:49154
abnormal phalanx morphology J:49154
abnormal rostral-caudal axis patterning J:49154
abnormal sternocostal joint morphology J:49154
abnormal tail morphology J:49154
abnormal tarsal bone morphology J:49154
cervical vertebral transformation J:49154
decreased caudal vertebrae number J:49154
embryonic lethality during organogenesis, incomplete penetrance J:49154
lethality throughout fetal growth and development, incomplete penetrance J:49154
lumbar vertebral transformation J:49154
neonatal lethality, complete penetrance J:49154
sacral vertebral transformation J:49154
small second pharyngeal arch J:49154
vertebral transformation J:49154
Fgfr1tm4Sor/Fgfr1tm4Sor
involves: 129S4/SvJaeSor * C57BL/6J
embryonic lethality, complete penetrance J:105920
Fgfr1tm5.1Jrt/Fgfr1tm5.1Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
no abnormal phenotype detected J:49154
Fgfr1tm5.1Sor/Fgfr1tm5.1Sor
H2az2Tg(Wnt1-cre)11Rth/H2az2+
129S4.Cg-Fgfr1tm5.1Sor H2az2Tg(Wnt1-cre)11Rth
midline facial cleft J:226497
Fgfr1tm5.1Sor/Fgfr1tm9.1Sor
H2az2Tg(Wnt1-cre)11Rth/H2az2+
129S4.Cg-Fgfr1tm5.1Sor Fgfr1tm9.1Sor H2az2Tg(Wnt1-cre)11Rth
cleft palate J:226497
Fgfr1tm5.1Sor/Fgfr1tm10.1Sor
H2az2Tg(Wnt1-cre)11Rth/H2az2+
129S4.Cg-Fgfr1tm5.1Sor Fgfr1tm10.1Sor H2az2Tg(Wnt1-cre)11Rth
cleft palate J:226497
Fgfr1tm5.2Sor/Fgfr1tm5.2Sor
129S4/SvJaeSor-Fgfr1tm5.2Sor
abnormal blastocyst morphology J:226497
abnormal developmental patterning J:226497
abnormal embryonic epiblast morphology J:226497
abnormal primitive endoderm morphology J:226497
embryonic lethality, complete penetrance J:226497
Fgfr1tm5.2Sor/Fgfr1tm5.2Sor
involves: 129S4/SvJaeSor * C57BL/6J
abnormal developmental patterning J:105920
abnormal gastrulation movements J:105920
abnormal mesoderm development J:105920
caudal body truncation J:105920
craniorachischisis J:105920
decreased paraxial mesoderm size J:105920
embryonic growth retardation J:105920
embryonic lethality during organogenesis, complete penetrance J:105920
enlarged heart J:105920
failure of heart looping J:105920
failure of somite differentiation J:105920
increased axial mesoderm size J:105920
Fgfr1tm5Jrt/Fgfr1tm5Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal craniofacial bone morphology J:49154
abnormal lateral plate mesoderm morphology J:49154
abnormal limb morphology J:49154
abnormal neural fold morphology J:49154
abnormal somite development J:49154
abnormal sternocostal joint morphology J:49154
abnormal tail morphology J:49154
broad limb buds J:49154
caudal body truncation J:49154
cervical vertebral transformation J:49154
decreased caudal vertebrae number J:49154
fusion of atlas and occipital bones J:49154
neonatal lethality J:49154
prenatal lethality, incomplete penetrance J:49154
rib fusion J:49154
small second pharyngeal arch J:49154
thoracic vertebral transformation J:49154
Fgfr1tm6.1Jrt/Fgfr1tm6.1Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal sternocostal joint morphology J:49154
abnormal vertebrae morphology J:49154
cervical vertebral transformation J:49154
lumbar vertebral transformation J:49154
rib fusion J:49154
sacral vertebral transformation J:49154
thoracic vertebral transformation J:49154
Fgfr1tm6Jrt/Fgfr1tm6Jrt
involves: 129S1/Sv * 129X1/SvJ
abnormal cerebellum vermis morphology J:83004
decreased inferior colliculus size J:83004
Fgfr1tm6Jrt/Fgfr1tm6Jrt
involves: 129S1/Sv * 129X1/SvJ * CD-1
abnormal axial skeleton morphology J:49154
abnormal craniofacial bone morphology J:49154
abnormal lateral plate mesoderm morphology J:49154
abnormal limb morphology J:49154
abnormal neural fold formation J:49154
abnormal somite development J:49154
abnormal sternocostal joint morphology J:49154
broad limb buds J:49154
caudal body truncation J:49154
cervical vertebral transformation J:49154
decreased caudal vertebrae number J:49154
decreased somite size J:49154
embryonic lethality during organogenesis, incomplete penetrance J:49154
fusion of atlas and occipital bones J:49154
neonatal lethality, complete penetrance J:49154
perinatal lethality, incomplete penetrance J:49154
rib fusion J:49154
small second pharyngeal arch J:49154
thoracic vertebral transformation J:49154
vertebral transformation J:49154
Fgfr1tm6Jrt/Fgfr1tm6Jrt
involves: 129S1/Sv * 129X1/SvJ * ICR
abnormal cochlear hair cell development J:78879
abnormal cochlear hair cell morphology J:78879
abnormal cochlear sensory epithelium morphology J:78879
abnormal orientation of inner hair cell stereociliary bundles J:78879
absent cochlear outer hair cells J:78879
absent organ of Corti supporting cells J:78879
increased cochlear inner hair cell number J:78879
neonatal lethality, complete penetrance J:78879
Fgfr1tm7.1Sor/Fgfr1tm7.1Sor
129S4/SvJaeSor-Fgfr1tm7.1Sor
normal no abnormal phenotype detected J:226497
Fgfr1tm8.1Sor/Fgfr1tm8.1Sor
129S4/SvJaeSor-Fgfr1tm8.1Sor
abnormal axial skeleton morphology J:226497
abnormal rib morphology J:226497
abnormal thoracic cage morphology J:226497
abnormal thoracic vertebrae morphology J:226497
decreased lumbar vertebrae number J:226497
decreased thoracic vertebrae number J:226497
normal growth/size/body region phenotype J:226497
normal homeostasis/metabolism phenotype J:226497
rib bifurcation J:226497
Fgfr1tm9.1Sor/Fgfr1tm9.1Sor
129S4/SvJaeSor-Fgfr1tm9.1Sor
cleft palate J:226497
increased thoracic vertebrae number J:226497
incus hypoplasia J:226497
lumbar vertebral transformation J:226497
malleus hypoplasia J:226497
middle ear ossicle hypoplasia J:226497
postaxial polydactyly J:226497
postnatal lethality, complete penetrance J:226497
second pharyngeal arch hypoplasia J:226497
stapes hypoplasia J:226497
styloid process hypoplasia J:226497
tympanic ring hypoplasia J:226497
Fgfr1tm10.1Sor/Fgfr1tm10.1Sor
129S4/SvJaeSor-Fgfr1tm10.1Sor
abnormal embryo development J:226497
abnormal neural crest cell migration J:226497
abnormal somite development J:226497
absent second pharyngeal arch J:226497
bleb J:226497
caudal body truncation J:226497
decreased somite size J:226497
embryonic growth arrest J:226497
embryonic growth retardation J:226497
embryonic lethality, complete penetrance J:226497
Tg(Gnrh1-Fgfr1)1Tsai/Tg(Gnrh1-Fgfr1)1Tsai
involves: C57BL/6J * DBA/2J
abnormal hypothalamus secretion J:95057
abnormal neuron morphology J:95057
decreased litter size J:95057
decreased neuron number J:95057
decreased testis weight J:95057
delayed vaginal opening J:95057
early reproductive senescence J:95057
normal homeostasis/metabolism phenotype J:95057

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory