48 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Emx1tm1Sia/Emx1tm1Sia Emx2tm1Sia/Emx2+ involves: C57BL/6 * CBA	abnormal cerebral cortex morphology	J:163926
	abnormal embryonic/fetal subventricular zone morphology	J:163926
Emx1tm1Sia/Emx1tm1Sia Emx2tm1Sia/Emx2tm1Sia involves: C57BL/6 * CBA	abnormal pallium development	J:163926
	absent dentate gyrus	J:163926
	absent hippocampal fimbria	J:163926
	absent hippocampus	J:163926
Emx2tm1Sia/Emx2+ Otx2tm1Sia/Otx2+ involves: C57BL/6 * CBA	abnormal forebrain morphology	J:70745
Emx2tm1Sia/Emx2tm1Sia Otx1tm1Sia/Otx1tm1Sia involves: C57BL/6 * CBA	abnormal Ammon gyrus morphology	J:98539
	abnormal cerebral cortex morphology	J:98539
	abnormal forebrain morphology	J:98539
	abnormal hippocampus morphology	J:98539
	abnormal pretectal region morphology	J:98539
	abnormal telencephalon morphology	J:98539
	small thalamus	J:98539
Emx2tm1Sia/Emx2tm1Sia Otx2tm1Sia/Otx2+ involves: C57BL/6 * CBA	abnormal adenohypophysis morphology	J:70745
	abnormal Ammon gyrus morphology	J:70745
	abnormal anterior commissure morphology	J:70745
	abnormal cerebral cortex morphology	J:70745, J:98539
	abnormal corpus callosum morphology	J:70745
	abnormal forebrain development	J:163926
	abnormal forebrain morphology	J:70745
	abnormal hippocampal fornix morphology	J:70745
	abnormal hippocampus region morphology	J:70745
	abnormal lateral ganglionic eminence morphology	J:70745
	abnormal lens morphology	J:70745
	abnormal medial ganglionic eminence morphology	J:70745
	abnormal midbrain morphology	J:70745
	abnormal midbrain-hindbrain boundary morphology	J:70745
	abnormal olfactory bulb mitral cell layer morphology	J:70745
	abnormal olfactory sensory neuron morphology	J:70745
	abnormal posterior commissure morphology	J:70745
	abnormal pretectal region morphology	J:70745
	abnormal telencephalon morphology	J:70745, J:98539
	abnormal thalamus morphology	J:70745
	absent choroid plexus	J:70745, J:98539
	absent dentate gyrus	J:70745
	absent hippocampal fimbria	J:70745
	absent hippocampus	J:70745, J:98539
	enlarged tectum	J:70745
	lethality throughout fetal growth and development, complete penetrance	J:70745
	retina hyperplasia	J:70745
	small olfactory bulb	J:70745
Emx2tm1Sia/Emx2tm1Sia Otx2tm7Sia/Otx2tm7Sia involves: C57BL/6NCrlj * CBA/JNCrlj	absent diencephalon	J:91012
Emx2tm1Sia/Emx2tm1Sia Pax6Sey/Pax6Sey involves: C57BL/6 * CBA	abnormal Ammon gyrus morphology	J:98539
	abnormal brain commissure morphology	J:98539
	abnormal brain morphology	J:98539
	abnormal cerebral cortex morphology	J:98539
	abnormal embryonic/fetal subventricular zone morphology	J:98539
	abnormal pretectal region morphology	J:98539
	abnormal tectum morphology	J:98539
	abnormal telencephalon morphology	J:98539
	abnormal thalamus morphology	J:98539
	absent choroid plexus	J:98539
	absent diencephalon	J:98539
	absent hippocampus	J:98539
Setdb1tm1.1Yshk/Setdb1tm1.1Yshk Emx2tm2(cre)Sia/Emx2+ involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal astrocyte morphology	J:188109
	abnormal cerebral cortex morphology	J:188109
	abnormal cortical plate morphology	J:188109
	abnormal nervous system development	J:188109
	abnormal neuron differentiation	J:188109
	abnormal neuronal precursor proliferation	J:188109
	abnormal telencephalon development	J:188109
	decreased neuron number	J:188109
	decreased neuronal precursor cell number	J:188109
	increased neuron apoptosis	J:188109
	increased neuron number	J:188109
	loss of cortex neurons	J:188109
	postnatal lethality, complete penetrance	J:188109