Eif2b4 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
MGI:95300

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Eif2b4^tm1.1Vdk/Eif2b4⁺ Eif2b5^tm1.1Vdk/Eif2b5^tm1.1Vdk involves: C57BL/6 * C57BL/6J	abnormal astrocyte morphology	J:234659
	abnormal axon morphology	J:234659
	abnormal cerebellum white matter morphology	J:234659
	abnormal myelination	J:234659
	abnormal retina morphology	J:234659
	ataxia	J:234659
	brain vacuoles	J:234659
	decreased body weight	J:234659
	premature death	J:234659
	sporadic seizures	J:234659
Eif2b4^tm1.1Vdk/Eif2b4^tm1.1Vdk Eif2b5^tm1.1Vdk/Eif2b5⁺ involves: C57BL/6 * C57BL/6J	abnormal astrocyte morphology	J:234659
	abnormal axon morphology	J:234659
	abnormal cerebellum white matter morphology	J:234659
	abnormal myelination	J:234659
	abnormal retina morphology	J:234659
	ataxia	J:234659
	brain vacuoles	J:234659
	decreased body weight	J:234659
	premature death	J:234659
	sporadic seizures	J:234659
Eif2b4^tm1.1Vdk/Eif2b4^tm1.1Vdk Eif2b5^tm1.1Vdk/Eif2b5^tm1.1Vdk involves: C57BL/6 * C57BL/6J	abnormal cerebellum white matter morphology	J:234659
	abnormal forebrain morphology	J:234659
	abnormal myelination	J:234659
	abnormal retina inner nuclear layer morphology	J:234659
	abnormal retina morphology	J:234659
	abnormal retina outer nuclear layer morphology	J:234659
	ataxia	J:234659
	brain vacuoles	J:234659
	decreased body weight	J:234659
	decreased oligodendrocyte number	J:234659
	ectopic Bergmann glia cells	J:234659
	increased oligodendrocyte progenitor number	J:234659
	lethality at weaning	J:234659
	sporadic seizures	J:234659
	thin retina inner plexiform layer	J:234659

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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