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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hlcs
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
MGI:894646
12 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hlcsem1(IMPC)J/Hlcs+
C57BL/6NJ-Hlcsem1(IMPC)J/Mmjax 		decreased circulating calcium level J:211773
decreased circulating phosphate level J:211773
Hlcsem1(IMPC)J/Hlcsem1(IMPC)J
C57BL/6NJ-Hlcsem1(IMPC)J/Mmjax 		abnormal egg cylinder morphology J:279207
absent head fold J:279207
absent primitive node J:279207
decreased embryo size J:279207
embryonic growth arrest J:279207
embryonic lethality prior to organogenesis J:211773, J:279207
embryonic lethality, complete penetrance J:279207
failure of primitive streak formation J:279207
failure to gastrulate J:279207
preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory