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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sstr5
somatostatin receptor 5
MGI:894282
16 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Sstr5tm1Fcb/Sstr5tm1Fcb
involves: 129
abnormal pancreatic alpha cell morphology J:179577
normal homeostasis/metabolism phenotype J:179577
increased insulin secretion J:179577
Sstr5tm1Fcb/Sstr5tm1Fcb
involves: 129 * C57BL/6J
decreased pancreatic beta cell number J:91762
Sstr5tm1Fcb/Sstr5tm2Fcb
Tg(Ins2-cre)1Heed/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA
abnormal insulin clearance J:99786
decreased circulating glucose level J:99786
decreased insulin secretion J:99786
decreased pancreatic delta cell number J:99786
impaired glucose tolerance J:99786
increased circulating insulin level J:99786
increased insulin secretion J:99786
Sstr5tm1Hawi/Sstr5tm1Hawi
involves: 129S7/SvEvBrd * C57BL/6J
decreased body weight J:101259
decreased circulating glucose level J:101259
decreased circulating insulin level J:101259
improved glucose tolerance J:101259
increased circulating glucagon level J:101259
increased circulating leptin level J:101259
increased insulin secretion J:101259
increased insulin sensitivity J:101259

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory