Neurog3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Neurog3
neurogenin 3
MGI:893591

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Neurog3^{tm1(Neurog3,cre/ERT)Ggu}/Neurog3^{tm1(Neurog3,cre/ERT)Ggu} Tg(Ins2-cre)25Mgn/0 involves: 129S6/SvEvTac * C57BL/6 * DBA	increased circulating glucose level	J:150074
Neurog3^{tm1(Neurog3,cre/ERT)Ggu}/Neurog3^{tm1(Neurog3,cre/ERT)Ggu} Tg(Pdx1-cre/Esr1*)1Mga/0 involves: 129S6/SvEvTac	abnormal pancreatic beta cell physiology	J:150074
	impaired glucose tolerance	J:150074
Neurog3^{tm1(Neurog3,cre/ERT)Ggu}/Neurog3^{tm1.1(cre/ERT)Ggu} involves: 129S6/SvEvTac	impaired glucose tolerance	J:150074
Neurog3^{tm1(Neurog3,cre/ERT)Ggu}/Neurog3^{tm1.1(cre/ERT)Ggu} Tg(Ins2-cre)25Mgn/0 involves: 129S6/SvEvTac * C57BL/6 * DBA	increased circulating glucose level	J:150074
Neurog3^{tm1(Neurog3,cre/ERT)Ggu}/Neurog3^{tm1.1(cre/ERT)Ggu} Tg(Pdx1-cre/Esr1*)1Mga/0 involves: 129S6/SvEvTac	abnormal circulating insulin level	J:150074
	hyperglycemia	J:150074
	impaired glucose tolerance	J:150074
	increased circulating glucose level	J:150074
Neurog3^{tm1.1(cre/ERT)Ggu}/Neurog3⁺ Pdx1^tm1Macd/Pdx1⁺ Tg(tetO-Myt1)2Ggu/0 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ	abnormal pancreatic islet morphology	J:136131
Tg(Pdx1-Neurog3)1Heed/? involves: C57BL/6 * CBA	abnormal pancreas development	J:57072

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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