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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Dok1
docking protein 1
MGI:893587
28 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Dok1tm1Ppp/Dok1+
Tg(BCR/ABL1)5Hhi/0
involves: 129S1/Sv
increased leukemia incidence J:95334
premature death J:95334
Dok1tm1Ppp/Dok1tm1Ppp
Dok2tm1Ppp/Dok2tm1Ppp
129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp
abnormal leukocyte physiology J:95334
enlarged spleen J:95334
increased bone marrow cell number J:95334
increased leukemia incidence J:95334
increased leukocyte cell number J:95334
increased lung adenocarcinoma incidence J:158011
increased monocyte cell number J:95334
increased neutrophil cell number J:95334
Dok1tm1Ppp/Dok1tm1Ppp
Dok2tm1Ppp/Dok2tm1Ppp
Dok3tm1Ppp/Dok3tm1Ppp
129S1/Sv-Dok1tm1Ppp Dok2tm1Ppp Dok3tm1Ppp
abnormal pulmonary alveolus morphology J:158011
increased bronchioalveolar stem cell number J:158011
increased chronic myelocytic leukemia incidence J:158011
increased leukocyte cell number J:158011
increased lung adenocarcinoma incidence J:158011
increased lung tumor incidence J:158011
increased type II pneumocyte number J:158011
premature death J:158011
pulmonary hyperplasia J:158011
Dok1tm1Ppp/Dok1tm1Ppp
Dok3tm1Ppp/Dok3tm1Ppp
129S1/Sv-Dok1tm1Ppp Dok3tm1Ppp
increased lung adenocarcinoma incidence J:158011
Dok1tm1Ppp/Dok1tm1Ppp
Tg(BCR/ABL1)5Hhi/0
involves: 129S1/Sv
increased leukemia incidence J:95334
premature death J:95334
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
B6.129-Dok1tm1Yyam Dok2tm1Yyam
abnormal leukocyte physiology J:95335
abnormal myelopoiesis J:95335
enlarged spleen J:95335
extramedullary hematopoiesis J:95335
increased erythroblast number J:95335
increased leukemia incidence J:95335
increased leukocyte cell number J:95335
increased megakaryocyte cell number J:95335
increased monocyte cell number J:95335
increased neutrophil cell number J:95335
increased sarcoma incidence J:95335
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
abnormal macrophage physiology J:163407
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
Dok3tm1Brs/Dok3tm1Brs
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
abnormal macrophage physiology J:163407
increased histiocytic sarcoma incidence J:163407
increased macrophage cell number J:163407
increased tumor incidence J:163407
premature death J:163407
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6
enlarged lymph nodes J:95335
enlarged thymus J:95335
increased leukemia incidence J:95335
premature death J:95335
Dok1tm1Yyam/Dok1tm1Yyam
Ppargtm1Laz/Ppargtm1Laz
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
abnormal fat cell morphology J:133566
normal adipose tissue phenotype J:133566
Dok1tm1Yyam/Dok1tm1Yyam
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6
enlarged lymph nodes J:95335
enlarged thymus J:95335
increased leukemia incidence J:95335
premature death J:95335

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory