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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ctsg
cathepsin G
MGI:88563
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ctsgtm1.1Roes/Ctsgtm1.1Roes
Elanetm1(cre)Roes/Elanetm1(cre)Roes
involves: 129P2/OlaHsd 		decreased susceptibility to endotoxin shock J:77597
increased susceptibility to fungal infection J:77597
Ctsgtm1Ley/Ctsgtm1Ley
Elanetm1Sds/Elanetm1Sds
B6.129X1-Elanetm1Sds Ctsgtm1Ley 		normal immune system phenotype J:131520
Ctsgtm1Ley/Ctsgtm1Ley
Elanetm1Sds/Elanetm1Sds
involves: 129X1/SvJ 		normal hematopoietic system phenotype J:131496
normal immune system phenotype J:131496
Ctsgtm2(PML/RARA)Ley/Ctsgtm2(PML/RARA)Ley
involves: 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:84230
Ctsgtm2.1(PML/RARA)Ley/Ctsg+
involves: 129 * 129X1/SvJ * C57BL/6 		abnormal bone marrow cell morphology/development J:166479
abnormal common myeloid progenitor cell morphology J:166479
abnormal spleen morphology J:166479
enlarged spleen J:166479
increased acute promyelocytic leukemia incidence J:166479
increased spleen weight J:166479
premature death J:166479
Ctsgtm2.1(PML/RARA)Ley/Ctsg+
involves: 129X1/SvJ * C57BL/6 		abnormal myelopoiesis J:84230, J:86458
anemia J:84230
enlarged liver J:84230
enlarged spleen J:84230
extramedullary hematopoiesis J:84230
increased leukemia incidence J:84230, J:86458
increased leukocyte cell number J:84230
thrombocytopenia J:84230
Ctsgtm2.1(PML/RARA)Ley/Ctsg+
Elanetm1Sds/Elanetm1Sds
involves: 129S/SvEv * 129X1/SvJ * C57BL/6 		abnormal myelopoiesis J:86458
increased leukemia incidence J:86458
Ctsgtm2.1(PML/RARA)Ley/Ctsgtm2.1(PML/RARA)Ley
involves: 129X1/SvJ * C57BL/6 		increased leukemia incidence J:84230
Ctsgtm3.1(PML/RARA)Ley/Ctsg+
involves: 129 * C57BL/6 		abnormal bone marrow cell morphology/development J:166479
abnormal common myeloid progenitor cell morphology J:166479
abnormal spleen morphology J:166479
enlarged spleen J:166479
increased acute promyelocytic leukemia incidence J:166479
increased spleen weight J:166479
premature death J:166479
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory