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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Csk
c-src tyrosine kinase
MGI:88537
53 phenotypes from 6 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Csktm1Sia/Csk+
involves: BALB/c * C57BL/6 * CBA
no abnormal phenotype detected J:12623
Csktm1Sia/Csktm1Sia
involves: BALB/c * C57BL/6 * CBA
abnormal cranial ganglia morphology J:12623
abnormal embryonic neuroepithelium morphology J:12623
abnormal heart development J:12623
abnormal neural tube morphology J:12623
abnormal otic vesicle development J:12623
absent nasal placodes J:12623
absent optic placodes J:12623
absent visceral yolk sac blood islands J:12623
absent vitelline blood vessels J:12623
cellular necrosis J:12623
normal cellular phenotype J:12623
decreased embryo size J:12623
decreased embryonic neuroepithelium thickness J:12623
delayed neural tube closure J:12623
embryo tissue necrosis J:12623
embryonic growth arrest J:12623
embryonic growth retardation J:12623
embryonic lethality during organogenesis, complete penetrance J:12623
incomplete caudal neuropore closure J:12623
incomplete embryo turning J:12623
incomplete rostral neuropore closure J:12623
Csktm1Sor/Csk+
129P2.129S7-Csktm1Sor
abnormal food preference J:188631
abnormal object recognition memory J:188631
abnormal social investigation J:188631
decreased anxiety-related response J:188631
Csktm1Sor/Csktm1Sor
either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
abnormal allantois morphology J:12622
abnormal cephalic neural fold morphology J:12622
absent notochord J:12622
caudal body truncation J:12622
decreased embryo size J:12622
embryonic lethality during organogenesis, complete penetrance J:12622
enlarged allantois J:12622
incomplete embryo turning J:12622
incomplete rostral neuropore closure J:12622
megacephaly J:12622
open neural tube J:12622
poor circulation J:12622
wavy neural tube J:12622
Csktm1Tara/Csktm1Tara
Tg(Mx1-cre)1Cgn/0
involves: 129P2/OlaHsd * C57BL/6 * CB20 * CBA
abnormal CD4-positive T cell differentiation J:49654
absent CD8-positive, alpha-beta T cells J:49654
enlarged thymus J:49654
Csktm1Tara/Csktm2Tara
Elanetm1(cre)Roes/Elane+
involves: 129P2/OlaHsd * CB20 * C57BL/6
abnormal granulocyte physiology J:89716
abnormal myelopoiesis J:89716
increased acute inflammation J:89716
increased susceptibility to bacterial infection J:89716
Csktm2b(EUCOMM)Hmgu/Csk+
C57BL/6N-Csktm2b(EUCOMM)Hmgu/Bay
abnormal retina inner nuclear layer morphology J:211773
abnormal retina vasculature morphology J:211773
decreased total retina thickness J:211773
Csktm2b(EUCOMM)Hmgu/Csktm2b(EUCOMM)Hmgu
C57BL/6N-Csktm2b(EUCOMM)Hmgu/Bay
abnormal embryo development J:211773
abnormal embryo size J:211773
abnormal embryo turning J:211773
abnormal neural tube closure J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Csktm2Sia/Csktm2Sia
involves: BALB/c * C57BL/6 * CBA
abnormal cranial ganglia morphology J:12623
abnormal lens induction J:12623
abnormal neural tube morphology J:12623
abnormal otic vesicle development J:12623
absent olfactory bulb J:12623
absent visceral yolk sac blood islands J:12623
absent vitelline blood vessels J:12623
cellular necrosis J:12623
normal cellular phenotype J:12623
decreased embryo size J:12623
embryo tissue necrosis J:12623
embryonic growth arrest J:12623
embryonic growth retardation J:12623
embryonic lethality during organogenesis, complete penetrance J:12623
incomplete embryo turning J:12623
incomplete rostral neuropore closure J:12623
open neural tube J:12623

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory