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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cr1l
complement component (3b/4b) receptor 1-like
MGI:88513
25 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cr1ltm1.1Song/Cr1ltm1.1Song
Tg(Cd4-cre)1Cwi/0
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL
decreased CD4-positive, alpha beta T cell number J:146538
decreased CD8-positive, alpha-beta T cell number J:146538
decreased lymphocyte cell number J:146538
increased B cell number J:146538
lymph node hypoplasia J:146538
Cr1ltm1.1Song/Cr1ltm1.1Song
Tg(Lck-cre)548Jxm/0
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL
decreased CD4-positive, alpha beta T cell number J:146538
decreased CD8-positive, alpha-beta T cell number J:146538
decreased lymphocyte cell number J:146538
increased B cell number J:146538
lymph node hypoplasia J:146538
Cr1ltm1b(KOMP)Wtsi/Cr1l+
B6N(Cg)-Cr1ltm1b(KOMP)Wtsi/J
abnormal retinal blood vessel morphology J:211773
increased grip strength J:211773
increased mean corpuscular hemoglobin J:211773
Cr1ltm1b(KOMP)Wtsi/Cr1ltm1b(KOMP)Wtsi
B6N(Cg)-Cr1ltm1b(KOMP)Wtsi/J
abnormal embryo size J:211773
abnormal embryo turning J:211773
abnormal neural tube morphology J:211773
embryonic growth retardation J:211773
preweaning lethality, complete penetrance J:211773
Cr1ltm1Hmo/Cr1l+
involves: 129X1/SvJ
abnormal proximal convoluted tubule morphology J:105466
increased blood urea nitrogen level J:105466
increased susceptibility to kidney reperfusion injury J:105466
Cr1ltm1Hmo/Cr1ltm1Hmo
involves: 129X1/SvJ
abnormal ectoplacental cone morphology J:59432
abnormal hippocampus morphology J:197576
abnormal maternal decidual layer morphology J:59432
abnormal trophectoderm morphology J:59432
increased inflammatory response J:59432
lethality throughout fetal growth and development, complete penetrance J:59432
normal mortality/aging J:197576
Tg(Mt1-Crry)26Quig/?
involves: CD-1
abnormal inflammatory response J:117777
abnormal kidney physiology J:117777

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory