Crk Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crk
v-crk avian sarcoma virus CT10 oncogene homolog
MGI:88508

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crk^{Gt(pU-Hachi)8104Imeg}/Crk^{Gt(pU-Hachi)8104Imeg} involves: C57BL/6 * CBA	no abnormal phenotype detected	J:59071
Crk^tm1.1Cur/Crk^tm1.1Cur involves: 129S/SvEv * C57BL/6	abnormal common carotid artery morphology	J:111399
	abnormal heart ventricle morphology	J:111399
	abnormal nasal mucosa morphology	J:111399
	abnormal nose morphology	J:111399
	abnormal vascular smooth muscle morphology	J:111399
	cleft secondary palate	J:111399
	dilated heart left ventricle	J:111399
	dilated heart right ventricle	J:111399
	hemorrhage	J:111399
	hydrops fetalis	J:111399
	increased vasodilation	J:111399
	lethality throughout fetal growth and development, incomplete penetrance	J:111399
	palatal shelves fail to meet at midline	J:111399
	perinatal lethality, complete penetrance	J:111399
	thin ventricular wall	J:111399
Crk^tm1Cur/Crk^tm1Cur Tg(Nes-cre)1Kln/0 involves: 129S/SvEv * C57BL/6 * SJL	decreased body weight	J:143049
	normal nervous system phenotype	J:143049
	postnatal growth retardation	J:143049

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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