Cp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cp
ceruloplasmin
MGI:88476

40 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cp^m1Btlr/Cp^m1Btlr C57BL/6J-Cp^m1Btlr	decreased circulating iron level	J:173078
Cp^m1Btlr/Cp^m1Btlr C57BL/6J-Cp^m1Btlr	increased liver iron level	J:173078
Cp^m1Cbea/Cp^m1Cbea involves: C3H/DiSnA * C57BL/10ScSnA	hemochromatosis	J:122133
Cp^{tm1b(KOMP)Wtsi}/Cp^{tm1b(KOMP)Wtsi} B6N(Cg)-Cp^{tm1b(KOMP)Wtsi}/J	abnormal sensory capabilities/reflexes/nociception	J:211773
	abnormal sleep behavior	J:211773
	decreased circulating iron level	J:211773
	decreased hemoglobin content	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased mean corpuscular volume	J:211773
	hypoalgesia	J:211773
	increased heart weight	J:211773
Cp^tm1Hrs/Cp^tm1Hrs involves: 129X1/SvJ * Black Swiss	abnormal iron homeostasis	J:57730
	abnormal iron level	J:57730
	abnormal liver copper level	J:71807
	decreased circulating ceruloplasmin level	J:57730
	normal hematopoietic system phenotype	J:57730
	increased circulating ferritin level	J:57730
	increased liver iron level	J:57730, J:71807
	increased spleen iron level	J:57730
Cp^tm1Samd/Cp^tm1Samd involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal astrocyte morphology	J:112703
	abnormal astrocyte physiology	J:120651
	abnormal brain iron level	J:78092, J:112703
	abnormal cerebellar granule layer morphology	J:78092
	abnormal fourth ventricle morphology	J:112703
	abnormal lipid homeostasis	J:78092
	abnormal locomotor behavior	J:142344
	abnormal neuron morphology	J:78092
	abnormal Purkinje cell morphology	J:112703
	abnormal response to injury	J:142344
	abnormal retina inner nuclear layer morphology	J:78092
	decreased circulating iron level	J:78092
	decreased motor neuron number	J:142344
	demyelination	J:142344
	impaired coordination	J:78092
	increased cellular sensitivity to hydrogen peroxide	J:78092
	increased circulating unsaturated transferrin level	J:78092
	increased liver iron level	J:78092
	neuron degeneration	J:78092
Cp^tm1Yos/Cp^tm1Yos C.129P2-Cp^tm1Yos	abnormal gait	J:142713
	abnormal lipid homeostasis	J:142713
	abnormal locomotor activation	J:142713
Cp^tm1Yos/Cp^tm1Yos involves: 129P2/OlaHsd * BALB/c	abnormal hepatocyte morphology	J:79916
	abnormal Kupffer cell morphology	J:79916
	decreased circulating iron level	J:79916
	increased liver iron level	J:79916
	microcytic anemia	J:79916

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23