Vsx2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vsx2
visual system homeobox 2
MGI:88401

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn1b^tm1Mlf/Cdkn1b⁺ Vsx2^tm1.1Eml/Vsx2^tm1.1Eml involves: 129 * C57BL/6	abnormal eye morphology	J:190452
Fign^fi/Fign^fi Vsx2^or/Vsx2^or involves: C57BL/Gr	abnormal cell cycle checkpoint function	J:5575
Mitf^Mi/Mitf⁺ Vsx2^or-J/Vsx2^or-J involves: 129S1/Sv * 129X1/SvJ	abnormal eye morphology	J:190452
	abnormal eye size	J:190452
Mitf^Mi/Mitf⁺ Vsx2^tm1.1Itl/Vsx2^tm1.1Itl involves: 129S1/Sv * 129S6/SvEvTac	abnormal eye morphology	J:190452
	abnormal eye size	J:190452
Mitf^Mi/Mitf⁺ Vsx2^tm1.1Eml/Vsx2^tm1.1Eml involves: 129S1/Sv * 129X1/SvJ	abnormal eye morphology	J:190452
	abnormal eye size	J:190452
Shox2^{tm1.1(cre)Oki}/Shox2⁺ Tg(CAG-Bgeo/GFP)21Lbe/0 Vsx2^tm1(DTA)Kash/Vsx2⁺ involves: 129S/SvEv * 129X1/SvJ * C57BL/6J	abnormal nervous system physiology	J:209344
	abnormal spinal cord grey matter morphology	J:209344
Vsx2^or-J/Vsx2⁺ Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129/Sv * C57BL/6 * FVB/N * SJL	abnormal Muller cell morphology	J:91498
Vsx2^or-J/Vsx2^or-J Modor1^CASA/Rk/? involves: 129X1/SvJ * CASA/Rk	abnormal eye size	J:109796
Vsx2^or-J/Vsx2^or-J Modor2^CASA/Rk/? involves: 129S1/Sv * CASA/Rk	abnormal eye size	J:109796
Vsx2^or-J/Vsx2^or-J Modor3^CASA/Rk/? involves: 129S1/Sv * CASA/Rk	abnormal eye size	J:109796
Vsx2^or-J/Vsx2^or-J Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129S1/Sv * C57BL/6 * FVB/N * SJL	decreased retina rod cell number	J:91498
	disorganized retina layers	J:91498
	microphthalmia	J:91498
Vsx2^{tm1.1(DTA)Kash}/Vsx2⁺ involves: 129S4/SvJae * C57BL/6	abnormal nervous system physiology	J:145621
	abnormal spinal cord interneuron morphology	J:145621
	abnormal ventral interneuron 2 morphology	J:145621
	neonatal lethality, complete penetrance	J:145621

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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