Chrm3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chrm3
cholinergic receptor, muscarinic 3, cardiac
MGI:88398

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chrm1^tm1Jwe/Chrm1^tm1Jwe Chrm3^tm1Jwe/Chrm3^tm1Jwe involves: 129S6/SvEvTac * CF-1	normal nervous system phenotype	J:112505
Chrm1^tm1Kano/Chrm1^tm1Kano Chrm3^tm1Mmt/Chrm3^tm1Mmt involves: 129X1/SvJ * C57BL/6	abnormal inhibitory postsynaptic currents	J:98902
	abnormal submandibular gland physiology	J:105126
	decreased salivation	J:105126
Chrm2^tm1Jwe/Chrm2^tm1Jwe Chrm3^tm1Jwe/Chrm3^tm1Jwe involves: 129S4/SvJae * 129S6/SvEvTac * CF-1	normal respiratory system phenotype	J:104034
Chrm2^tm1Minm/Chrm2^tm1Minm Chrm3^tm1Mmt/Chrm3^tm1Mmt involves: 129X1/SvJ * C57BL/6	distended urinary bladder	J:99247
	impaired contractility of ileal smooth muscle	J:99247
	impaired smooth muscle contractility	J:99247
	mydriasis	J:99247
	postnatal growth retardation	J:99247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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