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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cebpb
CCAAT/enhancer binding protein beta
MGI:88373
59 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1(Cebpb)Ylee
involves: 129X1/SvJ * C57BL/6 * FVB/N 		abnormal brown adipose tissue morphology J:77646
abnormal fat cell morphology J:77646
abnormal hematopoietic system physiology J:77646
abnormal white adipose tissue morphology J:77646
decreased circulating leptin level J:77646
decreased white adipose tissue amount J:77646
normal growth/size/body region phenotype J:77646
normal homeostasis/metabolism phenotype J:77646
normal immune system phenotype J:77646
increased brown adipose tissue amount J:77646
increased food intake J:77646
normal reproductive system phenotype J:77646
Cebpatm1.1(Cebpb)Ylee/Cebpatm1.1Gonz
involves: 129X1/SvJ * C57BL/6 * FVB/N 		abnormal white adipose tissue morphology J:77646
decreased white adipose tissue amount J:77646
Cebpatm1Gonz/Cebpa+
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2 		normal integument phenotype J:154022
Cebpatm1Gonz/Cebpatm1Gonz
Cebpbtm1Es/Cebpbtm1Es
Tg(KRT14-cre/ERT)20Efu/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 		abnormal epidermal layer morphology J:158721
abnormal epidermis stratum basale morphology J:158721
abnormal epidermis stratum spinosum morphology J:158721
abnormal epidermis suprabasal layer morphology J:158721
abnormal eye morphology J:158721
abnormal hair follicle infundibulum morphology J:158721
abnormal keratinocyte differentiation J:158721
abnormal male preputial gland morphology J:158721
abnormal Meibomian gland morphology J:158721
abnormal sebaceous gland morphology J:158721
abnormal sebaceous lipid secretion J:158721
abnormal sebocyte differentiation J:158721
abnormal sebocyte morphology J:158721
dry eyes J:158721
epidermal hyperplasia J:158721
hair follicle outer root sheath hyperplasia J:158721
hyperkeratosis J:158721
increased keratinocyte proliferation J:158721
Meibomian gland atrophy J:158721
parakeratosis J:158721
Cebpatm1Gonz/Cebpatm1Gonz
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal epidermal layer morphology J:154022
eyelids open at birth J:154022
increased keratinocyte proliferation J:154022
neonatal lethality, complete penetrance J:154022
parakeratosis J:154022
shiny skin J:154022
tight skin J:154022
weight loss J:154022
Cebpatm1Gonz/Cebpatm2Nerl
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal epidermis stratum corneum morphology J:154022
abnormal epidermis stratum granulosum morphology J:154022
increased keratinocyte proliferation J:154022
shiny skin J:154022
Cebpatm1Gonz/Cebpatm9Nerl
Cebpbtm1Nerl/Cebpbtm1Nerl
Tg(KRT14-cre)1Cgn/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2 		absent epidermis stratum corneum J:154022
absent epidermis stratum granulosum J:154022
increased keratinocyte proliferation J:154022
parakeratosis J:154022
shiny skin J:154022
Cebpbtm1.1Maka/Cebpbtm1.1Maka
Ins2Akita/Ins2Akita
Tg(Ins2-cre)23Herr/0
involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NSlc * CBA/J 		abnormal pancreatic beta cell mass J:156725
abnormal pancreatic islet cell apoptosis J:156725
decreased circulating insulin level J:156725
decreased insulin secretion J:156725
increased circulating glucose level J:156725
Cebpbtm1.1Maka/Cebpbtm1.1Maka
Leprdb/Leprdb
Tg(Ins2-cre)23Herr/0
involves: 129P2/OlaHsd * C57BL/6J * C57BLKS/J * CBA/J 		abnormal pancreatic islet cell apoptosis J:156725
hyperglycemia J:156725
increased circulating insulin level J:156725
increased pancreatic beta cell mass J:156725
Cebpbtm1Kish/Cebpbtm1Kish
Cebpdtm1Aki/Cebpdtm1Aki
involves: 129P2/OlaHsd 		abnormal brown adipose tissue thermogenesis J:45062
abnormal brown fat cell morphology J:45062
abnormal brown fat lipid droplet number J:45062
abnormal cell differentiation J:45062
decreased epididymal fat pad weight J:45062
decreased white adipose tissue amount J:45062
neonatal lethality, complete penetrance J:45062
perinatal lethality, incomplete penetrance J:45062
Cebpbtm1Pfj/Cebpbtm1Pfj
Tg(Hba-x-v-Ha-ras)TG.ACLed/0
involves: C57BL/6 		decreased incidence of tumors by chemical induction J:73558
decreased tumor growth/size J:73558
Cebpbtm1Vpo/Cebpbtm1Vpo
Il6tm1Poli/Il6tm1Poli
involves: 129S/SvEv * MF1 		normal hematopoietic system phenotype J:35883
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory