Cdx2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdx2
caudal type homeobox 2
MGI:88361

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdx1^tm1Pgr/Cdx1^tm1Pgr Cdx2^tm2Fbe/Cdx2^tm2Fbe Tg(Cyp1a1-cre/ERT)1Dwi/0 involves: 129 * C57BL/6 * CBA	abnormal crypts of Lieberkuhn morphology	J:179732
Cdx2^tm1Fbe/Cdx2⁺ Cdx4^tm1.1Jdes/Y involves: 129 * C57BL/6 * CBA * FVB	abnormal allantois morphology	J:104372
	abnormal placenta labyrinth morphology	J:104372
	abnormal placenta morphology	J:104372
	abnormal placenta vasculature	J:104372
	absent placenta hemotrichorial membrane	J:104372
	edema	J:104372
	embryonic growth retardation	J:104372
	embryonic lethality during organogenesis, complete penetrance	J:104372
	failure of chorioallantoic fusion	J:104372
	increased rib number	J:104372
	lumbar vertebral transformation	J:104372
	sirenomelia	J:104372
	thoracic vertebral transformation	J:104372
	vertebral transformation	J:104372
Cdx2^tm1Fbe/Cdx2⁺ Cdx4^tm1.1Jdes/Cdx4⁺ involves: 129 * C57BL/6 * CBA * FVB	abnormal placenta labyrinth morphology	J:104372
	failure of chorioallantoic fusion	J:104372
Cdx2^tm1Mmt/Cdx2⁺ Apc^tm1Mmt/Apc⁺ B6.129-Cdx2^tm1Mmt Apc^tm1Mmt	abnormal cell cycle checkpoint function	J:86737
	abnormal chromosome morphology	J:86737
	abnormal colon morphology	J:86737
	abnormal small intestine morphology	J:86737
	colon polyps	J:86737
	decreased apoptosis	J:86737
	increased apoptosis	J:86737

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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