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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cdh2
cadherin 2
MGI:88355
57 phenotypes from 5 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cdh2em1Obir/Cdh2em1Obir
C57BL/6JRcc-Cdh2em1Obir
abnormal prepulse inhibition J:331911
abnormal sensorimotor gating J:331911
abnormal synapse morphology J:331911
abnormal synaptic vesicle clustering J:331911
abnormal synaptic vesicle number J:331911
abnormal synaptic vesicle recycling J:331911
decreased aggression towards male mice J:331911
decreased dopaminergic neuron number J:331911
decreased exploration in new environment J:331911
decreased miniature excitatory postsynaptic current frequency J:331911
decreased nervous system dopamine level J:331911
decreased neurotransmitter release J:331911
hyperactivity J:331911
impaired synaptic plasticity J:331911
increased startle reflex J:331911
Cdh2em2Obir/Cdh2em2Obir
C57BL/6JRcc-Cdh2em2Obir
hyperactivity J:331911
Cdh2Gt(OST49160)Lex/Cdh2Gt(OST49160)Lex
involves: 129S5/SvEvBrd
abnormal brain development J:95209
abnormal heart tube morphology J:95209
pericardial edema J:95209
prenatal lethality, complete penetrance J:95209
Cdh2tm1Glr/Cdh2Gt(OST49160)Lex
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: 129S5/SvEvBrd * 129S6/SvEvTac * C57BL/6J * FVB/N
abnormal cardiovascular system morphology J:98828
abnormal cardiovascular system physiology J:98828
abnormal heart shape J:98828
abnormal impulse conducting system conduction J:98828
abnormal intercalated disk morphology J:98828
abnormal myocardial fiber morphology J:98828
decreased cardiac output J:98828
decreased heart rate J:98828
decreased ventricle muscle contractility J:98828
dilated heart atrium J:98828
dilated heart left ventricle J:98828
dilated heart right ventricle J:98828
increased heart rate J:98828
irregular heartbeat J:98828
premature death J:98828
Cdh2tm1Glr/Cdh2tm1Glr
Emx1tm1(cre)Krj/Emx1+
involves: 129S6/SvEvTac * C57BL/6
abnormal cerebral cortex morphology J:215584
abnormal cortical ventricular zone morphology J:215584
abnormal neocortex morphology J:215584
abnormal nervous system tract morphology J:215584
abnormal radial glial cell morphology J:215584
ectopic neuron J:215584
increased neuronal precursor cell number J:215584
thickened cerebral cortex J:215584
Cdh2tm1Glr/Cdh2tm1Glr
Olig2tm1(cre)Tmj/Olig2+
involves: 129S6/SvEvTac
abnormal neuronal migration J:178688
abnormal spinal cord morphology J:178688
abnormal spinal cord motor column morphology J:178688
lethality throughout fetal growth and development, incomplete penetrance J:178688
neonatal lethality, complete penetrance J:178688
Cdh2tm1Glr/Cdh2tm1Hyn
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: 129S6/SvEvTac * C57BL/6J * FVB/N
abnormal cardiovascular system morphology J:98828
abnormal cardiovascular system physiology J:98828
abnormal heart shape J:98828
abnormal impulse conducting system conduction J:98828
abnormal intercalated disk morphology J:98828
abnormal myocardial fiber morphology J:98828
decreased cardiac output J:98828
decreased heart rate J:98828
decreased ventricle muscle contractility J:98828
dilated heart atrium J:98828
dilated heart left ventricle J:98828
dilated heart right ventricle J:98828
increased heart rate J:98828
irregular heartbeat J:98828
premature death J:98828
Cdh2tm1Hyn/Cdh2tm1Hyn
involves: 129S2/SvPas
abnormal embryo turning J:37888
abnormal heart tube morphology J:37888
abnormal myocardial fiber morphology J:37888
abnormal myocardium layer morphology J:37888
abnormal somite shape J:37888, J:58409
abnormal visceral yolk sac morphology J:37888
abnormal vitelline vasculature morphology J:37888
distended pericardium J:37888
embryonic growth retardation J:37888
embryonic lethality during organogenesis, complete penetrance J:37888
enlarged heart J:37888
wavy neural tube J:37888

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory