Cd69 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd69
CD69 antigen
MGI:88343

17 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd69^tm1Fsm/Cd69^tm1Fsm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal B cell differentiation	J:61329
	abnormal humoral immune response	J:61329
	normal hematopoietic system phenotype	J:61329
	normal immune system phenotype	J:61329
	increased IgG2a level	J:61329
	increased IgM level	J:61329
	increased immature B cell number	J:61329
	increased pre-B cell number	J:61329
Cd69^tm1Naka/Cd69^tm1Naka B6.129P2-Cd69^tm1Naka	abnormal CD4-positive, alpha-beta T cell physiology	J:184704
	abnormal humoral immune response	J:184704
	abnormal memory T cell physiology	J:184704
	abnormal T cell physiology	J:184704
	decreased CD4-positive, alpha-beta T cell number	J:184704
	decreased interferon-gamma secretion	J:184704
	decreased tumor necrosis factor secretion	J:184704
Cd69^tm1Naka/Cd69^tm1Naka C.129P2-Cd69^tm1Naka	decreased susceptibility to induced arthritis	J:84940
	impaired neutrophil chemotaxis	J:84940
	impaired neutrophil recruitment	J:84940

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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