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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cacna1b
calcium channel, voltage-dependent, N type, alpha 1B subunit
MGI:88296
62 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cacna1btm1.1Dili/Cacna1btm1.1Dili
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
abnormal single cell response J:165258
normal behavior/neurological phenotype J:165258
postnatal lethality, incomplete penetrance J:165258
Cacna1btm1b(KOMP)Wtsi/Cacna1btm1b(KOMP)Wtsi
C57BL/6N-Cacna1btm1b(KOMP)Wtsi/H
abnormal behavior J:211773
abnormal gait J:211773
abnormal locomotor behavior J:211773
decreased anxiety-related response J:211773
decreased fasting circulating glucose level J:211773
decreased grip strength J:211773
decreased thigmotaxis J:211773
hyperactivity J:211773
increased exploration in new environment J:211773
Cacna1btm1Hssh/Cacna1btm1Hssh
involves: 129S4/SvJae * C57BL/6J
abnormal channel response J:71480
abnormal conditioned taste aversion behavior J:96593
abnormal discrimination learning J:137285
abnormal excitatory postsynaptic potential J:137285
abnormal hypothalamus secretion J:147238
abnormal inhibitory postsynaptic currents J:147238
abnormal learning/memory/conditioning J:137285
abnormal long-term spatial reference memory J:137285
abnormal miniature excitatory postsynaptic currents J:137285
abnormal miniature inhibitory postsynaptic currents J:147238
abnormal nervous system electrophysiology J:147238
abnormal sensory capabilities/reflexes/nociception J:71480
abnormal single cell response J:147238
abnormal spatial learning J:137285
abnormal summary potential J:147238
abnormal synaptic transmission J:147238
alcohol aversion J:96593
normal behavior/neurological phenotype J:71480
decreased alcohol consumption J:96593
enhanced behavioral response to alcohol J:96593
normal homeostasis/metabolism phenotype J:96593
hyporesponsive to tactile stimuli J:71480
impaired behavioral response to alcohol J:96593
impaired conditioned place preference behavior J:96593
impaired social transmission of food preference J:137285
increased aggression towards mice J:147238
increased chemical nociceptive threshold J:71480
increased thermal nociceptive threshold J:71480
normal nervous system phenotype J:71480
reduced long-term potentiation J:137285
Cacna1btm1Ksw/Cacna1btm1Ksw
involves: C57BL/6 * CBA
abnormal baroreceptor physiology J:76458
abnormal channel response J:103705
abnormal frequency of paradoxical sleep J:84684
abnormal lipid level J:105212
abnormal sleep duration J:84684
abnormal sleep pattern J:84684
abnormal sympathetic nervous system physiology J:76458
normal behavior/neurological phenotype J:103705
decreased circulating glucagon level J:105212
decreased circulating insulin level J:105212
decreased circulating leptin level J:105212
decreased circulating triglyceride level J:105212
decreased susceptibility to diet-induced obesity J:105212
normal endocrine/exocrine gland phenotype J:105212
fragmentation of sleep/wake states J:84684
normal growth/size/body region phenotype J:103705
normal homeostasis/metabolism phenotype J:84684, J:105212
hyperactivity J:84684
hypertension J:76458
improved glucose tolerance J:105212
increased chemical nociceptive threshold J:103705
increased heart rate J:76458
increased thermal nociceptive threshold J:103705
Cacna1btm1Ttan/Cacna1btm1Ttan
involves: 129S4/SvJae * C57BL/6
abnormal behavioral response to xenobiotic J:107971
abnormal excitatory postsynaptic potential J:107971
decreased anxiety-related response J:69585
decreased startle reflex J:69585
hyporesponsive to tactile stimuli J:69585
increased chemical nociceptive threshold J:69585
normal nervous system phenotype J:69585
preweaning lethality, incomplete penetrance J:69585
Cacna1btm2.1Dili/Cacna1btm2.1Dili
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
abnormal single cell response J:165258
decreased chemically-elicited antinociception J:165258
Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/0
C57BL/6J-Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan
normal behavior/neurological phenotype J:221994
decreased susceptibility to injury J:221994

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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory