Cbx2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cbx2
chromobox 2
MGI:88289

25 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cbx2^{tm1b(KOMP)Wtsi}/Cbx2⁺ C57BL/6N-Cbx2^{tm1b(KOMP)Wtsi}/H	increased grip strength	J:211773
	persistence of hyaloid vascular system	J:211773
Cbx2^{tm1b(KOMP)Wtsi}/Cbx2^{tm1b(KOMP)Wtsi} C57BL/6N-Cbx2^{tm1b(KOMP)Wtsi}/H	preweaning lethality, complete penetrance	J:211773
Cbx2^tm1Cim/Cbx2^tm1Cim (129P2/Ola x BALB/c)F1	abnormal body weight	J:38487
	neonatal lethality, incomplete penetrance	J:38487
	postnatal lethality, incomplete penetrance	J:38487
Cbx2^tm1Cim/Cbx2^tm1Cim involves: 129P2/OlaHsd * BALB/c	abnormal body weight	J:38487
	abnormal cervical atlas morphology	J:38487
	abnormal scapula morphology	J:38487
	abnormal skeleton morphology	J:38487
	arrested T cell differentiation	J:38487
	decreased fibroblast proliferation	J:38487
	decreased rib number	J:38487
	decreased splenocyte proliferation	J:38487
	decreased sternebra number	J:38487
	fusion of atlas and occipital bones	J:38487
	neonatal lethality, incomplete penetrance	J:38487
	postnatal lethality, incomplete penetrance	J:38487
	premature death	J:38487
	secondary sex reversal	J:48123
	vertebral transformation	J:38487
Cbx2^tm1Ykf/Cbx2⁺ involves: 129S2/SvPas * C57BL/6NJcl	vertebral transformation	J:48123
Cbx2^tm1Ykf/Cbx2^tm1Ykf involves: 129S2/SvPas * C57BL/6NJcl	abnormal body weight	J:48123
	abnormal colon morphology	J:48123
	abnormal primary sex determination	J:48123
	abnormal secondary sex determination	J:48123
	agonadal	J:48123
	malocclusion	J:48123
	postnatal lethality, incomplete penetrance	J:48123
	premature death	J:48123
	secondary sex reversal	J:48123
	small ovary	J:48123
	true hermaphroditism	J:48123
	vertebral transformation	J:48123

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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