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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cbs
cystathionine beta-synthase
MGI:88285
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Cbstm1Unc/Cbstm1Unc
Tg(Mt1-CBS)25Waku/0
involves: 129P2/OlaHsd * C3H * C57BL/6 		decreased body weight J:168131
increased circulating homocysteine level J:168131
increased circulating methionine level J:168131
increased circulating tumor necrosis factor level J:168131
increased Ly6C high monocyte number J:168131
increased monocyte cell number J:168131
increased susceptibility to atherosclerosis J:168131
Cbstm1Unc/Cbstm1Unc
Tg(CBS)11181Eri/0
involves: 129P2/OlaHsd * C57BL/6J 		abnormal blood homeostasis J:165612
abnormal circulating amino acid level J:165612
abnormal circulating homocysteine level J:165612
abnormal liver morphology J:165612
decreased bleeding time J:165612
decreased survivor rate J:165612
hypercoagulability J:165612
premature death J:165612
Cbstm1Unc/Cbstm1Unc
Tg(Mt1-CBS)25Waku/0
involves: 129P2/OlaHsd * C3H * C57BL/6 		abnormal amino acid level J:150548
abnormal circulating homocysteine level J:150548
Cbstm1Unc/Cbstm1Unc
Tg(Mt1-CBS*I278T)1Waku/0
involves: 129P2/OlaHsd * C3H * C57BL/6 		abnormal amino acid level J:150548
abnormal circulating homocysteine level J:150548
Cbstm1Unc/Cbstm1Unc
Tg(Mt1-CBS*S466L)EB86Waku/0
involves: 129P2/OlaHsd * C3H * C57BL/6 		increased circulating homocysteine level J:150548, J:168131
increased circulating methionine level J:168131
increased Ly6C high monocyte number J:168131
increased monocyte cell number J:168131
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory