Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
increased granulosa cell tumor incidence |
J:186144
|
|
increased testis tumor incidence |
J:186144
|
|
male infertility |
J:186144
|
|
seminiferous tubule degeneration |
J:186144
|
|
testicular atrophy |
J:186144
|
Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
|
abnormal Mullerian duct morphology |
J:171430
|
|
abnormal sex determination |
J:171430
|
|
failure of Mullerian duct regression |
J:171430
|
Axin2tm1.1(cre/ERT2/tdTomato)Eem/Axin2+
Ctnnb1tm2Kem/Ctnnb1tm2Kem
involves: 129S2/SvPas * C57BL/6
|
decreased cell proliferation |
J:204142
|
Bmi1tm1(cre/ERT)Mrc/Bmi1+
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal crypts of Lieberkuhn morphology |
J:138364
|
|
increased intestinal adenoma incidence |
J:138364
|
|
premature death |
J:138364
|
Ctnnb1Bfc/Ctnnb1+
either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
|
abnormal eye morphology |
J:170646
|
|
abnormal head morphology |
J:170646
|
|
anophthalmia |
J:170646
|
|
cataract |
J:170646
|
|
flattened snout |
J:170646
|
|
forebrain hypoplasia |
J:170646
|
|
microphthalmia |
J:170646
|
|
preweaning lethality, incomplete penetrance |
J:170646
|
Ctnnb1Bfc/Ctnnb1+
involves: BALB/cCrl * C3H/HeNCrl
|
abnormal globus pallidus morphology |
J:209611
|
|
abnormal hippocampus neuron morphology |
J:209611
|
|
abnormal operant conditioning behavior |
J:209611
|
|
abnormal spatial reference memory |
J:209611
|
|
abnormal synaptic vesicle clustering |
J:209611
|
|
abnormal vocalization |
J:209611
|
|
broad head |
J:63816,
J:209611
|
|
decreased corpus callosum size |
J:209611
|
|
decreased prepulse inhibition |
J:209611
|
|
enlarged thalamus |
J:209611
|
|
impaired contextual conditioning behavior |
J:209611
|
|
impaired coordination |
J:209611
|
|
increased brain size |
J:209611
|
|
increased striatum size |
J:209611
|
|
ocular hypertelorism |
J:63816
|
|
reduced long-term potentiation |
J:209611
|
|
small cerebellum |
J:209611
|
|
small olfactory bulb |
J:209611
|
Ctnnb1Bfc/Ctnnb1Bfc
either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
|
abnormal head size |
J:170646
|
|
preweaning lethality, complete penetrance |
J:170646
|
Ctnnb1em1V/Ctnnb1em1V
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
involves: C57BL/6 * C57BL/6J * CBA
|
abnormal retina development |
J:328283
|
|
decreased angiogenesis |
J:328283
|
Ctnnb1tm1.1Smoc/Ctnnb1tm1.1Smoc
Sox9em1(cre/ERT2)Tchn/Sox9+
involves: C57BL/6
|
increased incidence of tumors by chemical induction |
J:322311
|
Ctnnb1tm1Kba/Ctnnb1tm1Kba
involves: 129S6/SvEvTac * C57BL/6
|
abnormal craniofacial development |
J:178971
|
|
abnormal forebrain development |
J:178971
|
|
decreased embryo size |
J:178971
|
|
embryonic growth retardation |
J:178971
|
|
small pharyngeal arch |
J:178971
|
Ctnnb1tm1Max/Ctnnb1tm1Max
involves: 129 * 129S1/Sv * 129X1/SvJ
|
abnormal embryonic epiblast morphology |
J:29881
|
|
abnormal extraembryonic tissue morphology |
J:29881
|
|
abnormal germ layer development |
J:29881
|
|
absent allantois |
J:29881
|
|
absent amniotic folds |
J:29881
|
|
decreased embryo size |
J:29881
|
|
embryonic lethality during organogenesis, complete penetrance |
J:29881
|
Ctnnb1tm1Max/Ctnnb1tm2Kem
Tg(Msx2-cre)5Rem/0
involves: 129S1/Sv * 129X1/SvJ
|
abnormal apical ectodermal ridge morphology |
J:81795
|
|
abnormal forelimb morphology |
J:81795
|
|
abnormal humerus morphology |
J:81795
|
|
abnormal suckling behavior |
J:81795
|
|
abnormal ulna morphology |
J:81795
|
|
absent deltoid tuberosity |
J:81795
|
|
absent hindlimb |
J:81795
|
|
increased ectoderm apoptosis |
J:81795
|
|
neonatal lethality, complete penetrance |
J:81795
|
Ctnnb1tm1Max/Ctnnb1tm2Kem
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal bone mineralization |
J:114494
|
|
abnormal bone ossification |
J:114494
|
|
abnormal cartilage morphology |
J:114494
|
|
abnormal limb development |
J:114494
|
|
arrested osteoblast differentiation |
J:114494
|
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
|
abnormal small intestinal crypt cell proliferation |
J:169830
|
|
abnormal small intestine morphology |
J:169830
|
|
increased intestinal adenoma incidence |
J:169830
|
Ctnnb1tm1Mmt/Ctnnb1+
involves: 129X1/SvJ
|
no abnormal phenotype detected |
J:58367
|
Ctnnb1tm1Mmt/Ctnnb1+
Krt19tm1(cre)Mmt/Krt19+
involves: 129X1/SvJ
|
increased intestinal adenoma incidence |
J:58367
|
|
premature death |
J:58367
|
Ctnnb1tm1Mmt/Ctnnb1+
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129X1/SvJ
|
abnormal osteoclast differentiation |
J:178340
|
|
decreased bone marrow cell number |
J:178340
|
|
decreased bone resorption |
J:178340
|
|
increased bone volume |
J:178340
|
|
normal
skeleton phenotype |
J:178340
|
Ctnnb1tm1Mmt/Ctnnb1+
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * 129X1/SvJ
|
normal
neoplasm |
J:199091
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Pou3f4-cre)32Cren/?
involves: 129X1/SvJ
|
abnormal brain morphology |
J:83935
|
|
abnormal nervous system morphology |
J:83935
|
|
increased brain size |
J:83935
|
|
increased spinal cord size |
J:83935
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Col2a1-cre)1Bhr/0
involves: 129X1/SvJ
|
decreased length of long bones |
J:90567
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:90567
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA
|
abnormal trabecular bone morphology |
J:112659
|
|
increased hepatoblastoma incidence |
J:112659
|
|
premature death |
J:112659
|
|
skin fibrosis |
J:112659
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Wap-cre)11738Mam/0
FVB.Cg-Ctnnb1tm1Mmt Tg(Wap-cre)11738Mam
|
increased mammary gland tumor incidence in breeding females |
J:206839
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Pbsn-cre)4Prb/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
|
increased prostate gland adenocarcinoma incidence |
J:143034,
J:284956
|
|
increased prostate intraepithelial neoplasia incidence |
J:143034,
J:284956
|
|
premature death |
J:143034
|
|
squamous metaplasia of bulbourethral gland |
J:143034
|
|
squamous metaplasia of preputial gland |
J:143034
|
|
squamous metaplasia of urethral gland |
J:143034
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Tek-cre)1Ywa/0
involves: 129X1/SvJ * C57BL/6 * SJL
|
embryonic lethality, complete penetrance |
J:178340
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Cdh16-cre)91Igr/0
involves: 129X1/SvJ * ICR
|
dilated renal tubule |
J:151498
|
|
kidney cyst |
J:151498
|
|
postnatal lethality, complete penetrance |
J:151498
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Fabp1-cre)1Mmt/?
involves: 129X1/SvJ
|
increased intestinal adenoma incidence |
J:58367
|
|
premature death |
J:58367
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Hoxb7-cre)13Amc/0
involves: 129X1/SvJ * C57BL/6
|
abnormal kidney development |
J:160547
|
|
absent kidney |
J:160547
|
|
single kidney |
J:160547
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Col1a1-cre)1Kry/0
involves: 129X1/SvJ * FVB
|
absent lower incisors |
J:98430
|
|
decreased osteoclast cell number |
J:98430
|
|
increased bone mass |
J:98430
|
|
increased osteoma incidence |
J:98430
|
|
lethality at weaning, complete penetrance |
J:98430
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Upk2-cre)6Xrw/0
involves: 129X1/SvJ * FVB/N
|
abnormal urinary bladder urothelium morphology |
J:164579,
J:174242
|
|
normal
neoplasm |
J:164579,
J:174242
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129X1/SvJ * CD-1
|
abnormal bone ossification |
J:114494
|
|
abnormal long bone epiphyseal plate morphology |
J:114494
|
|
abnormal osteoblast differentiation |
J:114494
|
|
abnormal osteoclast differentiation |
J:114494
|
|
abnormal trabecular bone morphology |
J:114494
|
|
delayed intramembranous bone ossification |
J:114494
|
|
perinatal lethality, complete penetrance |
J:114494
|
|
premature endochondral bone ossification |
J:114494
|
|
short limbs |
J:114494
|
Ctnnb1tm1Mmt/Ctnnb1+
Ctsktm1(cre)Ska/Ctsk+
involves: 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
|
abnormal osteoclast differentiation |
J:178340
|
|
decreased bone marrow cell number |
J:178340
|
|
decreased bone resorption |
J:178340
|
|
increased bone volume |
J:178340
|
|
normal
skeleton phenotype |
J:178340
|
Ctnnb1tm1Mmt/Ctnnb1+
Lgr5tm1(cre/ERT2)Cle/Lgr5+
involves: 129P2/OlaHsd * 129X1/SvJ
|
intestine polyps |
J:193873
|
Ctnnb1tm1Mmt/Ctnnb1+
Nanos3tm2(cre)Ysa/Nanos3+
involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
|
abnormal seminiferous tubule morphology |
J:257319
|
|
abnormal spermatogonia morphology |
J:257319
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(CYP19A1-cre)1Jri/0
involves: 129X1/SvJ * C57BL/6
|
increased granulosa cell tumor incidence |
J:186144
|
|
increased ovary tumor incidence |
J:186144
|
|
premature death |
J:186144
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Tcfap2a-cre)1Will/0
involves: 129X1/SvJ * C57BL/6
|
abnormal cartilage development |
J:168016
|
|
abnormal eye morphology |
J:168016
|
|
abnormal face development |
J:168016
|
|
abnormal facial morphology |
J:168016
|
|
abnormal mandibular prominence morphology |
J:168016
|
|
abnormal maxillary prominence morphology |
J:168016
|
|
abnormal Meckel's cartilage morphology |
J:168016
|
|
abnormal medial nasal prominence morphology |
J:168016
|
|
abnormal oral cavity morphology |
J:168016
|
|
absent outer ear |
J:168016
|
|
absent vibrissae |
J:168016
|
|
ectopic cartilage |
J:168016
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:168016
|
|
lethality throughout fetal growth and development, incomplete penetrance |
J:168016
|
Ctnnb1tm1Mmt/Ctnnb1+
Dclk1tm1.1(cre/ERT2)Seno/Dclk1+
involves: 129X1/SvJ * C57BL/6
|
normal
neoplasm |
J:193873
|
Ctnnb1tm1Mmt/Ctnnb1+
Sox2tm1.1(cre/ERT2)Jpmb/Sox2+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
|
abnormal adenohypophysis morphology |
J:201265
|
|
increased pituitary gland tumor incidence |
J:201265
|
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Msx2-rtTA)885Lma/0
Tg(tetO-cre)1Jaw/0
involves: 129 * 129X1/SvJ * C57BL/6
|
abnormal craniofacial morphology |
J:202618
|
|
abnormal urinary bladder morphology |
J:202618
|
|
alopecia |
J:202618
|
|
increased urinary bladder carcinoma incidence |
J:202618
|
|
premature death |
J:202618
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
involves: 129X1/SvJ
|
no abnormal phenotype detected |
J:58367
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Gli1tm3(cre/ERT2)Alj/Gli1+
involves: 129S6/SvEvTac * 129X1/SvJ
|
abnormal external female genitalia morphology |
J:148515
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129X1/SvJ * C57BL/6 * CBA
|
abnormal muscle development |
J:124278
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Nanos3tm2(cre)Ysa/Nanos3+
involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
|
abnormal seminiferous tubule morphology |
J:257319
|
|
abnormal spermatogonia morphology |
J:257319
|
|
decreased testis weight |
J:257319
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Osr2tm5(cre)Jian/Osr2+
involves: 129X1/SvJ
|
abnormal dental mesenchyme morphology |
J:153554
|
|
abnormal tooth development |
J:153554
|
|
cleft palate |
J:153554
|
|
neonatal lethality |
J:153554
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129X1/SvJ
|
abnormal lung development |
J:204743
|
|
abnormal lung vasculature morphology |
J:204743
|
|
abnormal pulmonary artery morphology |
J:204743
|
|
abnormal pulmonary vein morphology |
J:204743
|
|
absent lungs |
J:204743
|
|
normal
cardiovascular system phenotype |
J:204743
|
|
tracheoesophageal fistula |
J:153098
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Tcf21tm1(cre)Seq/Tcf21+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal kidney development |
J:189643
|
|
hydroureter |
J:189643
|
|
kidney cyst |
J:189643
|
|
neonatal lethality |
J:189643
|
|
renal hypoplasia |
J:189643
|
|
ureter hypoplasia |
J:189643
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Tg(Cryaa-cre)10Mlr/0
involves: 129X1/SvJ * FVB/N
|
abnormal lens epithelium morphology |
J:152850
|
|
increased lens epithelium apoptosis |
J:152850
|
|
microphthalmia |
J:152850
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Tg(Msx2-cre)5Rem/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
ectopic limbs |
J:223057
|
|
polydactyly |
J:223057
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Tg(Mx1-cre)1Cgn/0
involves: 129S1/Sv * C57BL/6 * CBA
|
abnormal trabecular bone morphology |
J:112659
|
|
increased hepatoblastoma incidence |
J:112659
|
|
premature death |
J:112659
|
|
skin fibrosis |
J:112659
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Tg(Pitx1-cre)7Rsd/0
involves: 129X1/SvJ * BALB/c * C57BL/6
|
absent pituitary gland |
J:114817
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Tg(Upk2-cre)6Xrw/0
involves: 129X1/SvJ * FVB/N
|
abnormal urinary bladder urothelium morphology |
J:164579,
J:234236
|
|
normal
neoplasm |
J:164579
|
Ctnnb1tm1Wbm/Ctnnb1tm1Wbm
involves: 129P2/OlaHsd * C57BL/6
|
abnormal developmental patterning |
J:60391
|
|
abnormal ectoderm development |
J:60391
|
|
abnormal gastrulation |
J:60391
|
|
abnormal germ layer development |
J:60391
|
|
abnormal mesoderm development |
J:60391
|
|
abnormal proximal-distal axis patterning |
J:60391
|
|
abnormal rostral-caudal axis patterning |
J:60391
|
|
absent mesoderm |
J:60391
|
|
decreased embryo size |
J:60391
|
|
embryonic lethality during organogenesis, complete penetrance |
J:60391
|
|
failure to gastrulate |
J:60391
|
Ctnnb1tm1Yy/Ctnnb1tm1.1Yy
Tg(Col2a1-cre)1Bhr/0
involves: 129S6/SvEvTac * C57BL/6 * SJL
|
abnormal perichondrium morphology |
J:112462
|
|
decreased bone mineralization |
J:112462
|
|
failure of bone ossification |
J:112462
|
|
increased chondrocyte apoptosis |
J:112462
|
Ctnnb1tm1Yy/Ctnnb1tm1Yy
Tg(Col2a1-cre)1Bhr/0
involves: 129S6/SvEvTac * C57BL/6
|
domed cranium |
J:93028
|
|
fused synovial joints |
J:93028
|
|
neonatal lethality, complete penetrance |
J:93028
|
|
short limbs |
J:93028
|
Ctnnb1tm1Yy/Ctnnb1tm1Yy
Tg(Prnp-GFP/cre)1Blw/0
involves: 129S6/SvEvTac * C57BL/6
|
domed cranium |
J:93028
|
|
fused synovial joints |
J:93028
|
|
neonatal lethality, complete penetrance |
J:93028
|
|
short limbs |
J:93028
|
Ctnnb1tm1Yy/Ctnnb1tm1Yy
Tg(Prrx1-cre)1Cjt/0
involves: 129S6/SvEvTac * C57BL/6J * SJL/J
|
abnormal hair follicle development |
J:184918
|
|
abnormal ligament morphology |
J:184918
|
|
abnormal limb development |
J:184918
|
|
abnormal melanogenesis |
J:184918
|
|
abnormal tendon morphology |
J:184918
|
Ctnnb1tm1Yy/Ctnnb1tm1Yy
Twist2tm1(cre)Dor/Twist2+
involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6
|
fused synovial joints |
J:93028
|
Ctnnb1tm2.1Kem/Ctnnb1tm2.1Kem
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
|
abnormal inner cell mass morphology |
J:67966
|
|
absent mesoderm |
J:178971
|
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:178971
|
|
embryonic lethality, complete penetrance |
J:67966
|
Ctnnb1tm2Kem/Ctnnb1+
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
|
decreased trabecular bone volume |
J:178340
|
|
increased bone resorption |
J:178340
|
|
increased osteoclast cell number |
J:178340
|
|
osteoporosis |
J:178340
|
Ctnnb1tm2Kem/Ctnnb1+
Tg(Tek-cre)1Ywa/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
decreased trabecular bone volume |
J:178340
|
|
increased bone resorption |
J:178340
|
|
increased osteoclast cell number |
J:178340
|
|
osteoporosis |
J:178340
|
Ctnnb1tm2Kem/Ctnnb1+
Tg(Prrx1-cre)1Cjt/0
involves: 129 * C57BL/6 * SJL
|
abnormal skeleton morphology |
J:173242
|
Ctnnb1tm2Kem/Ctnnb1+
Ctsktm1(cre)Ska/Ctsk+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
|
decreased trabecular bone volume |
J:178340
|
|
increased bone resorption |
J:178340
|
|
increased osteoclast cell number |
J:178340
|
|
osteoporosis |
J:178340
|
Ctnnb1tm2Kem/Ctnnb1+
Osr2tm2(cre)Jian/Osr2+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal enamel knot morphology |
J:153554
|
|
cleft secondary palate |
J:153554
|
|
growth retardation of incisors |
J:153554
|
|
growth retardation of molars |
J:153554
|
|
neonatal lethality |
J:153554
|
Ctnnb1tm2Kem/Ctnnb1+
Nanos3tm2(cre)Ysa/Nanos3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
|
abnormal seminiferous tubule morphology |
J:257319
|
|
abnormal spermatogonia morphology |
J:257319
|
|
decreased testis weight |
J:257319
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
|
abnormal embryonic tissue morphology |
J:187739
|
|
prenatal lethality, complete penetrance |
J:187739
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129/Sv * C57BL/6 * CBA
|
abnormal brain development |
J:67966
|
|
abnormal brain morphology |
J:67966
|
|
abnormal cranial nerve morphology |
J:67966
|
|
abnormal dorsal root ganglion morphology |
J:67966
|
|
abnormal facial nerve morphology |
J:67966
|
|
abnormal glossopharyngeal nerve morphology |
J:67966
|
|
abnormal hindbrain morphology |
J:67966
|
|
abnormal hypoglossal nerve morphology |
J:67966
|
|
abnormal neural tube morphology |
J:67966
|
|
abnormal telencephalon morphology |
J:67966
|
|
abnormal trigeminal V mesencephalic nucleus morphology |
J:67966
|
|
abnormal vagus nerve morphology |
J:67966
|
|
absent cerebellum |
J:67966
|
|
absent choroid plexus |
J:67966
|
|
absent craniofacial bones |
J:67966
|
|
absent metencephalon |
J:67966
|
|
absent midbrain |
J:67966
|
|
absent midbrain-hindbrain boundary |
J:67966
|
|
absent oculomotor nerve |
J:67966
|
|
prenatal lethality, complete penetrance |
J:67966
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Kdrtm1(cre)Sato/Kdr+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal blood-brain barrier function |
J:142352
|
|
abnormal vasculogenesis |
J:142352
|
|
embryonic lethality during organogenesis, complete penetrance |
J:142352
|
|
intracranial hemorrhage |
J:142352
|
|
spinal hemorrhage |
J:142352
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Tg(Foxn1-cre)1Tbo/0
involves: 129S1/Sv * 129X1/SvJ
|
neonatal lethality, complete penetrance |
J:187739
|
|
skin lesions |
J:187739
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Tg(T-cre)1Lwd/0
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6
|
abnormal somite development |
J:200549
|
|
caudal body truncation |
J:200549
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Tg(T-cre/ERT2)1Lwd/0
involves: 129S1/Sv * 129X1/SvJ * C3H/HeNcr * C57BL/6NCr
|
abnormal axial mesoderm morphology |
J:200549
|
|
abnormal somite development |
J:200549
|
|
caudal body truncation |
J:200549
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Tg(Tek-cre)1Ywa/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
abnormal blood vessel morphology |
J:85505
|
|
abnormal endocardium morphology |
J:85505
|
|
abnormal placenta morphology |
J:85505
|
|
abnormal placental labyrinth vasculature morphology |
J:85505
|
|
abnormal umbilical cord blood vessel morphology |
J:85505
|
|
abnormal vascular endothelial cell morphology |
J:85505
|
|
abnormal visceral yolk sac morphology |
J:85505
|
|
abnormal vitelline vasculature morphology |
J:85505
|
|
embryonic lethality during organogenesis, complete penetrance |
J:85505
|
|
hemorrhage |
J:85505
|
|
pale yolk sac |
J:85505
|
|
pericardial edema |
J:85505
|
|
small heart |
J:85505
|
|
thin placenta labyrinth |
J:85505
|
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem
Tg(Zp3-cre)93Knw/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
|
abnormal embryonic tissue morphology |
J:187739
|
|
prenatal lethality, complete penetrance |
J:187739
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
|
decreased response of heart to induced stress |
J:109612
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Ctsktm1(cre)Ska/Ctsk+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
|
decreased trabecular bone volume |
J:178340
|
|
increased bone resorption |
J:178340
|
|
increased osteoclast cell number |
J:178340
|
|
osteoporosis |
J:178340
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Emx1tm1(cre)Yql/Emx1+
B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
|
abnormal cerebral cortex morphology |
J:92923
|
|
abnormal hippocampus morphology |
J:92923
|
|
abnormal nursing |
J:92923
|
|
absent corpus callosum |
J:92923
|
|
absent dentate gyrus |
J:92923
|
|
absent hippocampal commissure |
J:92923
|
|
absent hippocampus CA1 region |
J:92923
|
|
absent hippocampus CA2 region |
J:92923
|
|
absent hippocampus CA3 region |
J:92923
|
|
decreased body size |
J:92923
|
|
dilated lateral ventricle |
J:92923
|
|
increased susceptibility to pharmacologically induced seizures |
J:92923
|
|
male infertility |
J:92923
|
|
seizures |
J:92923
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129 * C57BL/6 * CBA/J
|
abnormal craniofacial morphology |
J:178971
|
|
abnormal neural tube morphology |
J:178971
|
|
abnormal telencephalon development |
J:178971
|
|
absent midbrain-hindbrain boundary |
J:178971
|
|
premature neuronal precursor differentiation |
J:178971
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
|
decreased trabecular bone volume |
J:178340
|
|
increased bone resorption |
J:178340
|
|
increased osteoclast cell number |
J:178340
|
|
osteoporosis |
J:178340
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Nanos3tm2(cre)Ysa/Nanos3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
|
abnormal seminiferous tubule morphology |
J:257319
|
|
abnormal spermatogonia morphology |
J:257319
|
|
decreased testis weight |
J:257319
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Olig2tm1(cre)Tmj/Olig2+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal spinal cord medial motor column morphology |
J:178688
|
|
decreased motor neuron number |
J:178688
|
|
neonatal lethality, complete penetrance |
J:178688
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Osr2tm2(cre)Jian/Osr2+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal joint morphology |
J:171478
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Pvalbtm1(cre)Arbr/Pvalb+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal head movements |
J:236989
|
|
abnormal nest building behavior |
J:236989
|
|
abnormal neuron physiology |
J:236989
|
|
abnormal response to social novelty |
J:236989
|
|
normal
behavior/neurological phenotype |
J:236989
|
|
enhanced spatial learning |
J:236989
|
|
impaired long-term object recognition memory |
J:236989
|
|
increased anxiety-related response |
J:236989
|
|
increased grooming behavior |
J:236989
|
|
increased thigmotaxis |
J:236989
|
|
slow extinction of fear memory |
J:236989
|
|
stereotypic behavior |
J:236989
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal lung development |
J:153098
|
|
absent lung buds |
J:153098
|
|
absent lungs |
J:153098
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tcf21tm1(cre)Seq/Tcf21+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal kidney development |
J:189643
|
|
fused kidneys |
J:189643
|
|
increased tumor incidence |
J:189643
|
|
prenatal lethality |
J:189643
|
|
renal hypoplasia |
J:189643
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Col1a1-cre)1Kry/0
involves: 129S1/Sv * 129X1/SvJ * FVB
|
decreased bone mass |
J:98430
|
|
increased osteoclast cell number |
J:98430
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Col2a1-cre)1Bhr/0
involves: 129S1/Sv * 129X1/SvJ
|
abnormal cartilage morphology |
J:90567
|
|
abnormal chondrocyte morphology |
J:90567
|
|
abnormal craniofacial bone morphology |
J:90567
|
|
decreased length of long bones |
J:90567
|
|
domed cranium |
J:90567
|
|
short limbs |
J:90567
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Col2a1-cre)3Amc/0
involves: 129S1/Sv * 129X1/SvJ
|
abnormal long bone morphology |
J:114494
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Cyp1a1-cre)1Dwi/0
involves: C57BL/6 * CBA
|
abnormal crypts of Lieberkuhn morphology |
J:92092
|
|
abnormal intestinal epithelium morphology |
J:92092
|
|
decreased Paneth cell number |
J:92092
|
|
ectopic Paneth cells |
J:92092
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Dct-lacZ)A12Jkn/0
Tg(Tyr-cre)1Lru/0
B6.Cg-Ctnnb1tm2Kem Tg(Tyr-cre)1Lru Tg(Dct-lacZ)A12Jkn
|
abnormal melanoblast morphology |
J:176245
|
|
decreased melanoblast proliferation |
J:176245
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Hoxb7-cre)5526Cmb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal kidney morphology |
J:136068
|
|
absent kidney |
J:136068
|
|
absent nephrogenic zone |
J:136068
|
|
decreased kidney cell proliferation |
J:136068
|
|
decreased kidney collecting duct number |
J:136068
|
|
decreased nephron number |
J:136068
|
|
hydroureter |
J:136068
|
|
impaired branching involved in ureteric bud morphogenesis |
J:136068
|
|
increased metanephric mesenchyme apoptosis |
J:136068
|
|
neonatal lethality, complete penetrance |
J:136068
|
|
small kidney |
J:136068
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Krt1-15-cre/PGR*)22Cot/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
abnormal hair cycle anagen phase |
J:204142
|
|
abnormal hair follicle morphology |
J:204142
|
|
abnormal hair growth |
J:204142
|
|
normal
integument phenotype |
J:204142
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(KRT5-rtTA)#Glk/0
Tg(tetO-cre)1Jaw/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
|
abnormal dermis papillary layer morphology |
J:204142
|
|
abnormal epidermal layer morphology |
J:204142
|
|
abnormal hair cycle anagen phase |
J:204142
|
|
abnormal hair follicle infundibulum morphology |
J:204142
|
|
abnormal hair follicle morphology |
J:204142
|
|
abnormal hair growth |
J:204142
|
|
abnormal keratinocyte morphology |
J:204142
|
|
accelerated hair follicle regression |
J:204142
|
|
decreased hair follicle number |
J:204142
|
|
hair follicle degeneration |
J:204142
|
|
increased hair follicle apoptosis |
J:204142
|
|
thick epidermis |
J:204142
|
|
thick epidermis stratum basale |
J:204142
|
|
thick epidermis suprabasal layer |
J:204142
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(KRT14-cre)#Smr/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
|
abnormal filiform papillae morphology |
J:242196
|
|
abnormal tongue morphology |
J:242196
|
|
decreased cell proliferation |
J:242196
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(KRT14-cre/ERT)20Efu/0
involves: 129S1/Sv * 129X1/SvJ * CD-1
|
abnormal epidermal layer morphology |
J:204142
|
|
cutaneous mastocytosis |
J:204142
|
|
normal
integument phenotype |
J:204142
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Msx2-cre)5Rem/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal autopod morphology |
J:223057
|
|
absent deltoid tuberosity |
J:223057
|
|
absent hindlimb |
J:223057
|
|
absent radius |
J:223057
|
|
decreased diameter of humerus |
J:223057
|
|
short ulna |
J:223057
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
|
abnormal retina vasculature morphology |
J:144980
|
|
abnormal vascular regression |
J:144980
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Pitx1-cre)7Rsd/0
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
|
abnormal adenohypophysis morphology |
J:114817
|
|
absent lactotrophs |
J:114817
|
|
absent somatotrophs |
J:114817
|
|
absent thyrotrophs |
J:114817
|
|
decreased gonadotroph cell number |
J:114817
|
|
increased corticotroph cell number |
J:114817
|
|
small adenohypophysis |
J:114817
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Tcfap2a-cre)1Will/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal face development |
J:168016
|
|
abnormal facial morphology |
J:168016
|
|
abnormal lateral nasal prominence morphology |
J:168016
|
|
abnormal lens development |
J:168016
|
|
abnormal mandibular prominence morphology |
J:168016
|
|
abnormal maxillary shelf morphology |
J:168016
|
|
abnormal maxillary zygomatic process morphology |
J:168016
|
|
abnormal medial nasal prominence morphology |
J:168016
|
|
abnormal nasal placode morphology |
J:168016
|
|
abnormal neurocranium morphology |
J:168016
|
|
abnormal optic eminence morphology |
J:168016
|
|
abnormal tympanic ring morphology |
J:168016
|
|
absent eyelids |
J:168016
|
|
absent hyoid bone |
J:168016
|
|
absent mandible |
J:168016
|
|
absent middle ear ossicles |
J:168016
|
|
fusion of basioccipital and basisphenoid bone |
J:168016
|
|
narrow frontonasal prominence |
J:168016
|
|
neonatal lethality, complete penetrance |
J:168016
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Tek-cre)1Ywa/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
|
decreased bone resorption |
J:178340
|
|
decreased osteoclast cell number |
J:178340
|
|
increased bone volume |
J:178340
|
|
osteopetrosis |
J:178340
|
|
prenatal lethality, incomplete penetrance |
J:178340
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Tg(Tyr-cre)1Lru/0
B6.Cg-Ctnnb1tm2Kem Tg(Tyr-cre)1Lru
|
abnormal hair follicle melanogenesis |
J:176245
|
|
abnormal pinna hair pigmentation |
J:176245
|
|
abnormal tail hair pigmentation |
J:176245
|
|
absent coat pigmentation |
J:176245
|
|
reduced hair shaft melanin granule number |
J:176245
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Twist2tm1(cre)Dor/Twist2+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal bone structure |
J:178499
|
|
abnormal cartilage morphology |
J:178499
|
|
abnormal joint morphology |
J:178499
|
|
abnormal skeleton morphology |
J:178499
|
|
arrested osteoblast differentiation |
J:178499
|
|
ectopic cartilage |
J:178499
|
|
failure of bone ossification |
J:178499
|
|
split sternum |
J:178499
|
Ctnnb1tm2Kem/Ctnnb1tm3Kba
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129 * C57BL/6 * CBA/J
|
abnormal craniofacial morphology |
J:178971
|
|
abnormal midbrain morphology |
J:178971
|
|
abnormal neuron differentiation |
J:178971
|
|
normal
embryo phenotype |
J:178971
|
Ctnnb1tm2Wbm/Ctnnb1tm2Wbm
involves: 129P2/OlaHsd * C57BL/6
|
abnormal developmental patterning |
J:60391
|
|
abnormal ectoderm development |
J:60391
|
|
abnormal gastrulation |
J:60391
|
|
abnormal germ layer development |
J:60391
|
|
abnormal mesoderm development |
J:60391
|
|
abnormal proximal-distal axis patterning |
J:60391
|
|
abnormal rostral-caudal axis patterning |
J:60391
|
|
absent mesoderm |
J:60391
|
|
decreased embryo size |
J:60391
|
|
embryonic lethality during organogenesis, complete penetrance |
J:60391
|
|
failure to gastrulate |
J:60391
|
Ctnnb1tm3Kba/Ctnnb1tm3Kba
involves: 129S6/SvEvTac * C57BL/6
|
abnormal gastrulation |
J:178971
|
|
absent mesoderm |
J:178971
|
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:178971
|
Ctnnb1tm3Wbm/Ctnnb1tm3Wbm
involves: 129P2/OlaHsd * C57BL/6
|
abnormal developmental patterning |
J:60391
|
|
abnormal ectoderm development |
J:60391
|
|
abnormal gastrulation |
J:60391
|
|
abnormal germ layer development |
J:60391
|
|
abnormal mesoderm development |
J:60391
|
|
abnormal proximal-distal axis patterning |
J:60391
|
|
abnormal rostral-caudal axis patterning |
J:60391
|
|
absent mesoderm |
J:60391
|
|
decreased embryo size |
J:60391
|
|
embryonic lethality during organogenesis, complete penetrance |
J:60391
|
|
failure to gastrulate |
J:60391
|
Ctnnb1tm4Wbm/Ctnnb1+
Tg(KRT14-cre)1Efu/0
involves: 129P2/OlaHsd
|
absent hair follicles |
J:186934
|
|
alopecia |
J:186934
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Gli1tm3(cre/ERT2)Alj/Gli1+
involves: 129P2/OlaHsd * 129S6/SvEvTac
|
abnormal external male genitalia morphology |
J:148515
|
|
abnormal foreskin morphology |
J:148515
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd
|
decreased gamma-delta T cell number |
J:202499
|
|
increased neutrophil cell number |
J:202499
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal hair growth |
J:69463
|
|
alopecia |
J:69463
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Krt14tm1.1(cre)Wbm/Krt14+
involves: 129P2/OlaHsd * C57BL/6
|
abnormal hair growth |
J:69463
|
|
alopecia |
J:69463
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Pax3tm1(cre)Joe/Pax3+
Not Specified
|
abnormal neural tube morphology |
J:96431
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(Cryaa-cre)10Mlr/?
involves: 129P2/OlaHsd * FVB/N
|
abnormal lens capsule morphology |
J:139969
|
|
abnormal lens epithelium morphology |
J:139969
|
|
disorganized secondary lens fibers |
J:139969
|
|
focal hair loss |
J:139969
|
|
loss of vibrissae |
J:139969
|
|
microphthalmia |
J:139969
|
|
ruptured lens capsule |
J:139969
|
|
small lens |
J:139969
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(Cryaa-cre,Tyr)39Mlr/?
involves: 129P2/OlaHsd * FVB/N
|
nuclear cataract |
J:139969
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(KRT14-cre)1Efu/0
involves: 129P2/OlaHsd
|
absent hair follicles |
J:155012
|
|
neonatal lethality, complete penetrance |
J:155012
|
|
thick epidermis |
J:155012
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(Pdx1-cre)6Tuv/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal exocrine pancreas morphology |
J:119908
|
|
abnormal pancreas morphology |
J:119908
|
|
abnormal pancreas physiology |
J:119908
|
|
decreased body size |
J:119908
|
|
decreased pancreas weight |
J:119908
|
|
pancreas fibrosis |
J:119908
|
|
pancreas inflammation |
J:119908
|
|
pancreatic acinar hypoplasia |
J:119908
|
|
premature death |
J:119908
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(Pou3f4-cre)32Cren/?
involves: 129P2/OlaHsd * C57BL/6
|
abnormal brain morphology |
J:83935
|
|
abnormal nervous system morphology |
J:83935
|
|
decreased brain size |
J:83935
|
|
decreased spinal cord size |
J:83935
|
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Tg(Prrx1-cre)98Mlgn/0
involves: 129P2/OlaHsd
|
abnormal forelimb morphology |
J:157917
|
|
abnormal hindlimb morphology |
J:157917
|
|
abnormal limb development |
J:157917
|
Gt(ROSA)26Sortm6(tetO-dTomato,-Ctnnb1*)Bgh/Gt(ROSA)26Sor+
involves: 129S6/SvEvTac * C57BL/6
|
abnormal cell physiology |
J:187862
|
Tg(Dct-lacZ)A12Jkn/0
Tg(Tyr-Ctnnb1/EGFP)#Lru/0
B6.Cg-Tg(Tyr-Ctnnb1/EGFP)#Lru Tg(Dct-lacZ)A12Jkn
|
abnormal melanoblast morphology |
J:176245
|
|
decreased melanoblast proliferation |
J:176245
|
Tg(Tyr-Ctnnb1/EGFP)#Lru/0
B6.Cg-Tg(Tyr-Ctnnb1/EGFP)#Lru
|
abnormal hair follicle melanogenesis |
J:176245
|
|
abnormal pinna hair pigmentation |
J:176245
|
|
abnormal tail hair pigmentation |
J:176245
|
|
diluted coat color |
J:176245
|
|
reduced hair shaft melanin granule number |
J:176245
|
Excel File
Analysis Tools