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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bmp2
bone morphogenetic protein 2
MGI:88177
57 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bmp2tm1Brd/Bmp2+
Bmp7tm1Kry/Bmp7+
Not Specified 		normal skeleton phenotype J:48538
Bmp2tm1Brd/Bmp2+
Tbx1tm1Pa/Tbx1+
involves: 129/Sv * C57BL/6 		abnormal pharyngeal arch artery morphology J:80764
Bmp2tm1Cjt/Bmp2+
Bmp7tm1Rob/Bmp7+
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		no abnormal phenotype detected J:118257
Bmp2tm1Cjt/Bmp2+
Bmp7tm1Rob/Bmp7tm1Rob
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		no abnormal phenotype detected J:118257
Bmp2tm1Cjt/Bmp2+
Bmp4tm1Jfm/Bmp4+
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		no abnormal phenotype detected J:118257
Bmp2tm1Cjt/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		polydactyly J:118257
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4+
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		abnormal skeleton development J:118257
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		abnormal apical ectodermal ridge morphology J:118257
abnormal autopod morphology J:118257
abnormal bone marrow cavity morphology J:118257
abnormal bone marrow development J:118257
abnormal bone ossification J:118257
abnormal cartilage development J:118257
abnormal digit morphology J:118257
abnormal forelimb stylopod morphology J:118257
abnormal forelimb zeugopod morphology J:118257
abnormal hindlimb stylopod morphology J:118257
abnormal hindlimb zeugopod morphology J:118257
abnormal interdigital cell death J:118257
abnormal long bone diaphysis morphology J:118257
broad limb buds J:118257
decreased autopod size J:118257
delayed bone ossification J:118257
delayed endochondral bone ossification J:118257
fused joints J:118257
syndactyly J:118257
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp7tm1Rob/Bmp7+
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal scapula morphology J:118257
Bmp2tm1Cjt/Bmp2tm1Cjt
Bmp7tm1Rob/Bmp7tm1Rob
Tg(Prrx1-cre)1Cjt/0
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal appendicular skeleton morphology J:118257
abnormal fibula morphology J:118257
abnormal phalanx morphology J:118257
abnormal scapula morphology J:118257
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		absent alisphenoid bone J:181229
cleft palate J:181229
decreased tympanic ring size J:181229
small temporal bone squamous part J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		cleft palate J:181229
decreased tympanic ring size J:181229
small alisphenoid bone J:181229
small nasal bone J:181229
small temporal bone squamous part J:181229
small zygomatic bone J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal tympanic ring morphology J:181229
cleft palate J:181229
small interparietal bone J:181229
small nasal bone J:181229
small temporal bone squamous part J:181229
small zygomatic bone J:181229
Bmp2tm1Jfm/Bmp2+
Bmp4tm1Jfm/Bmp4tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		small interparietal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4+
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal temporal bone squamous part morphology J:181229
abnormal tympanic ring morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent zygomatic bone J:181229
cleft palate J:181229
small nasal bone J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal interparietal bone morphology J:181229
abnormal mandibular angle morphology J:181229
abnormal mandibular condyloid process morphology J:181229
abnormal nasal bone morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent temporal bone squamous part J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Bmp7tm1Jfm/Bmp7tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal craniofacial bone morphology J:181229
abnormal interparietal bone morphology J:181229
abnormal mandible morphology J:181229
abnormal nasal bone morphology J:181229
absent alisphenoid bone J:181229
absent mandibular angle J:181229
absent mandibular condyloid process J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent temporal bone squamous part J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
large anterior fontanelle J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S4/SvJaeSor * C57BL/6J * CBA/J 		abnormal craniofacial bone morphology J:181229
abnormal interparietal bone morphology J:181229
abnormal mandible morphology J:181229
abnormal mandibular angle morphology J:181229
abnormal mandibular condyloid process morphology J:181229
abnormal nasal bone morphology J:181229
abnormal temporal bone squamous part morphology J:181229
absent alisphenoid bone J:181229
absent mandibular coronoid process J:181229
absent maxilla J:181229
absent tympanic ring J:181229
absent zygomatic bone J:181229
cleft palate J:181229
large anterior fontanelle J:181229
Bmp2tm1Jfm/Bmp2tm1Jfm
Bmp4tm1Jfm/Bmp4tm1Jfm
Tg(Mef2c-cre)2Blk/0
involves: 129S4/SvJaeSor 		abnormal heart ventricle outflow tract morphology J:169047
embryonic lethality during organogenesis, complete penetrance J:169047
pericardial edema J:169047
Bmp2tm1Jfm/Bmp2tm1Jfm
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J * CBA/J 		normal craniofacial phenotype J:274818
normal embryo phenotype J:274818
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory