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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Bcr
breakpoint cluster region
MGI:88141
70 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Abrtm1Jhg/Abrtm1Jhg
Bcrtm1Hkp/Bcrtm1Hkp
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Black Swiss * C57BL/6
abnormal astrocyte morphology J:72425
abnormal astrocyte physiology J:72425
abnormal cerebellar foliation J:72425
abnormal cerebellum morphology J:72425
abnormal CNS glial cell morphology J:72425
abnormal ear development J:108010
abnormal inner ear vestibule morphology J:108010
abnormal radial glial cell morphology J:72425
abnormal utricle morphology J:108010
abnormal vestibular saccule morphology J:108010
absent otoliths J:72425, J:108010
circling J:72425, J:108010
decreased otolith number J:108010
ectopic cerebellar granule cells J:72425
enlarged otoliths J:108010
gliosis J:72425
normal hearing/vestibular/ear phenotype J:108010
hyperactivity J:72425, J:108010
impaired balance J:108010
impaired coordination J:72425, J:108010
impaired swimming J:108010
neonatal lethality, incomplete penetrance J:72425
Bcrtm1(BCR/ABL)Tsr/Bcr+
Runx1tm3Dow/Runx1+
Tg(Vav1-cre)#Cgp/0
involves: C57BL/6
decreased lymphocyte cell number J:203111
increased monocyte cell number J:203111
increased neutrophil cell number J:203111
premature death J:203111
thrombocytopenia J:203111
Cbltm1Soga/Cbl+
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6 * DBA/2
premature death J:151543
Cbltm1Soga/Cbltm1Soga
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6 * DBA/2
enlarged lymph nodes J:151543
premature death J:151543
Crkltm1Hkp/Crkltm1Hkp
Tg(BCR/ABL)623Hkp/?
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * CBA
increased B cell derived lymphoma incidence J:76680
increased leukemia incidence J:76680
perinatal lethality, incomplete penetrance J:76680
premature death J:76680
Dok1tm1Ppp/Dok1+
Tg(BCR/ABL1)5Hhi/0
involves: 129S1/Sv
increased leukemia incidence J:95334
premature death J:95334
Dok1tm1Ppp/Dok1tm1Ppp
Tg(BCR/ABL1)5Hhi/0
involves: 129S1/Sv
increased leukemia incidence J:95334
premature death J:95334
Dok1tm1Yyam/Dok1tm1Yyam
Dok2tm1Yyam/Dok2tm1Yyam
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6
enlarged lymph nodes J:95335
enlarged thymus J:95335
increased leukemia incidence J:95335
premature death J:95335
Dok1tm1Yyam/Dok1tm1Yyam
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6
enlarged lymph nodes J:95335
enlarged thymus J:95335
increased leukemia incidence J:95335
premature death J:95335
Dok2tm1Ppp/Dok2+
Tg(BCR/ABL1)5Hhi/0
involves: 129S1/Sv
increased leukemia incidence J:95334
premature death J:95334
Dok2tm1Ppp/Dok2tm1Ppp
Tg(BCR/ABL1)5Hhi/0
involves: 129S1/Sv
increased leukemia incidence J:95334
premature death J:95334
Dok2tm1Yyam/Dok2tm1Yyam
Tg(BCR/ABL1)5Hhi/0
involves: C57BL/6
enlarged lymph nodes J:95335
enlarged thymus J:95335
increased leukemia incidence J:95335
premature death J:95335
Gt(ROSA)26Sortm4(CAG-hsb5)Nki/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0
Tg(Tal1-tTA)19Dgt/0
Tg(tetO-BCR/ABL1)2Dgt/0
TgTn(pb-sb-GrOnc)#aGsva/0
involves: 129P2/OlaHsd * C57BL/6 * CBA/J * DBA/2 * FVB/N
abnormal hematopoietic stem cell physiology J:227558
decreased hemoglobin content J:227558
increased basophil cell number J:227558
increased chronic myelocytic leukemia incidence J:227558
increased granulocyte number J:227558
increased hematopoietic stem cell number J:227558
increased leukocyte cell number J:227558
increased liver weight J:227558
increased myeloid cell number J:227558
increased spleen weight J:227558
premature death J:227558
Gt(ROSA)26Sortm4(CAG-hsb5)Nki/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/0
Tg(tetO-BCR/ABL1)2Dgt/0
TgTn(pb-sb-GrOnc)#aGsva/0
involves: 129P2/OlaHsd * C57BL/6 * CBA/J * FVB/N
increased leukemia incidence J:227558
premature death J:227558
Ikzf1tm1Kast/Ikzf1+
Tg(BCR/ABL)623Hkp/0
involves: 129S2/SvPas * C57BL/6 * CBA
increased acute lymphoblastic leukemia incidence J:160846
Rac3tm1Hkp/Rac3tm1Hkp
Tg(BCR/ABL)623Hkp/0
involves: C57BL/6 * C57BL/6J * CBA
increased leukemia incidence J:99168
premature death J:99168
Tg(BCR/ABL)623Hkp/?
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * CBA
increased B cell derived lymphoma incidence J:76680
increased leukemia incidence J:76680
premature death J:76680
Tg(BCR/ABL)623Hkp/0
involves: C57BL/6 * C57BL/6J * CBA
increased leukemia incidence J:99168
premature death J:99168
Tg(BCR/ABL)623Hkp/0
involves: C57BL/6 * CBA
increased acute lymphoblastic leukemia incidence J:160846
increased B cell derived lymphoma incidence J:89786
increased leukemia incidence J:89786
Tg(Ly6a-BCR/ABL1)IS1AIsg/0
involves: C57BL/6J * CBA
abnormal chromosome morphology J:144382
abnormal liver morphology J:144382
abnormal lung morphology J:144382
abnormal lymph node morphology J:144382
abnormal spleen morphology J:144382
increased chronic myelocytic leukemia incidence J:144382
increased hepatoma incidence J:144382
increased leukocyte cell number J:144382
increased lung adenocarcinoma incidence J:144382
increased neutrophil cell number J:144382
increased osteosarcoma incidence J:144382
increased spleen red pulp amount J:144382
increased spleen weight J:144382
increased testis tumor incidence J:144382
kidney failure J:144382
premature death J:144382
Tg(Ly6a-BCR/ABL1)IS1AIsg/0
Tg(Ly6a-BCR/ABL1)IS1BIsg/0
involves: C57BL/6J * CBA
increased leukemia incidence J:144382
premature death J:144382
Tg(Ly6a-BCR/ABL1)IS1BIsg/0
involves: C57BL/6J * CBA
abnormal chromosome morphology J:144382
abnormal liver morphology J:144382
abnormal lung morphology J:144382
abnormal lymph node morphology J:144382
abnormal spleen morphology J:144382
increased chronic myelocytic leukemia incidence J:144382
increased hepatoma incidence J:144382
increased leukocyte cell number J:144382
increased lung adenocarcinoma incidence J:144382
increased neutrophil cell number J:144382
increased osteosarcoma incidence J:144382
increased spleen red pulp amount J:144382
increased spleen weight J:144382
increased testis tumor incidence J:144382
kidney failure J:144382
premature death J:144382
Tg(Ly6a-TK,-BCR/ABL1)IS9AIsg/0
involves: C57BL/6J * CBA
increased chronic myelocytic leukemia incidence J:144382
increased leukocyte cell number J:144382
increased neutrophil cell number J:144382
premature death J:144382
Tg(Mx1-cre)1Cgn/0
Tg(Tal1-tTA)19Dgt/0
Tg(tetO-BCR/ABL1)2Dgt/0
TgTn(pb-sb-GrOnc)#aGsva/0
involves: C57BL/6 * CBA/J * DBA/2 * FVB/N
increased chronic myelocytic leukemia incidence J:227558
increased granulocyte number J:227558
increased leukocyte cell number J:227558
premature death J:227558
Tg(tetO-BCR/ABL1)2Dgt/0
Tg(MMTVtTA)1Mam/0
involves: C57BL/6 * FVB/N * SJL
abnormal bone marrow morphology J:72377
anemia J:72377
enlarged lymph nodes J:72377
enlarged spleen J:72377
increased apoptosis J:72377
increased leukemia incidence J:72377
increased leukocyte cell number J:72377
premature death J:72377
thrombocytopenia J:72377
Tg(tetO-BCR/ABL1)2Dgt/0
Tg(Tal1-tTA)19Dgt/0
involves: C57BL/6 * DBA/2 * FVB/N
abnormal common myeloid progenitor cell morphology J:96511
abnormal definitive hematopoiesis J:96511
abnormal lung morphology J:96511
abnormal lymph node morphology J:96511
abnormal lymphopoiesis J:96511
abnormal myeloblast morphology/development J:96511
abnormal small intestine morphology J:96511
abnormal spleen red pulp morphology J:96511
abnormal splenic cell ratio J:96511
enlarged liver J:96511
enlarged spleen J:96511
increased bone marrow cell number J:96511
increased hematopoietic stem cell number J:96511
increased leukocyte cell number J:96511
increased lymphoma incidence J:96511
increased megakaryocyte cell number J:96511
increased neutrophil cell number J:96511
increased sarcoma incidence J:96511
premature death J:96511

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory