Bcr Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bcr
BCR activator of RhoGEF and GTPase
MGI:88141

27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Abr^tm1Jhg/Abr^tm1Jhg Bcr^tm1Hkp/Bcr^tm1Hkp involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Black Swiss * C57BL/6	abnormal astrocyte morphology	J:72425
	abnormal astrocyte physiology	J:72425
	abnormal cerebellar foliation	J:72425
	abnormal cerebellum morphology	J:72425
	abnormal CNS glial cell morphology	J:72425
	abnormal ear development	J:108010
	abnormal inner ear vestibule morphology	J:108010
	abnormal radial glial cell morphology	J:72425
	abnormal utricle morphology	J:108010
	abnormal vestibular saccule morphology	J:108010
	absent otoliths	J:72425, J:108010
	circling	J:72425, J:108010
	decreased otolith number	J:108010
	ectopic cerebellar granule cells	J:72425
	enlarged otoliths	J:108010
	gliosis	J:72425
	normal hearing/vestibular/ear phenotype	J:108010
	hyperactivity	J:72425, J:108010
	impaired balance	J:108010
	impaired coordination	J:72425, J:108010
	impaired swimming	J:108010
	neonatal lethality, incomplete penetrance	J:72425
Bcr^{tm1(BCR/ABL)Tsr}/Bcr⁺ Runx1^tm3Dow/Runx1⁺ Tg(Vav1-cre)#Cgp/0 involves: C57BL/6	decreased lymphocyte cell number	J:203111
	increased monocyte cell number	J:203111
	increased neutrophil cell number	J:203111
	premature death	J:203111
	thrombocytopenia	J:203111

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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