73 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atp2a2tm1.1Iemr/Atp2a2+ Myl2tm1(cre)Krc/Myl2+ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6Crl * C57BL/6J	normal cardiovascular system phenotype	J:155628
Atp2a2tm1.1Iemr/Atp2a2tm1.1Iemr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ involves: 129P2/OlaHsd * C57BL/6J * FVB/N	abnormal cardiovascular system physiology	J:157143
	abnormal heart left atrium morphology	J:157143
	abnormal heart left ventricle pressure	J:157143
	abnormal myocardial fiber physiology	J:157143
	normal cardiovascular system phenotype	J:157143
	decreased cardiac muscle contractility	J:157143
	decreased cardiac output	J:157143
	decreased heart rate	J:157143
	decreased systemic arterial systolic blood pressure	J:157143
	dilated heart atrium	J:157143
	enlarged heart	J:157143
	increased circulating noradrenaline level	J:157143
Atp2a2tm1.1Iemr/Atp2a2tm1.1Iemr Tg(Myhca-cre)1Lrsn/0 involves: 129P2/OlaHsd * C57BL/6Crl * FVB	embryonic lethality during organogenesis, complete penetrance	J:155628
Atp2a2tm1.1Raco/Atp2a2+ C57BL/6J-Atp2a2tm1.1Raco/Raco	abnormal blood circulation	J:216004
	abnormal calcium ion homeostasis	J:216004
	abnormal physiological neovascularization	J:216004
	abnormal vascular endothelial cell migration	J:216004
	abnormal vascular endothelial cell physiology	J:216004
	decreased angiogenesis	J:216004
Atp2a2tm1.1Raco/Atp2a2tm1.1Raco C57BL/6J-Atp2a2tm1.1Raco/Raco	abnormal vascular development	J:216004
	decreased embryo size	J:216004
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:216004
Atp2a2tm1b(EUCOMM)Hmgu/Atp2a2+ C57BL/6N-Atp2a2tm1b(EUCOMM)Hmgu/H	decreased circulating alkaline phosphatase level	J:211773
	decreased mean platelet volume	J:211773
	increased fasting circulating glucose level	J:211773
Atp2a2tm1b(EUCOMM)Hmgu/Atp2a2tm1b(EUCOMM)Hmgu C57BL/6N-Atp2a2tm1b(EUCOMM)Hmgu/H	preweaning lethality, complete penetrance	J:211773
Atp2a2tm1Fwuy/Atp2a2tm1Fwuy involves: 129S1/Sv * 129X1/SvJ * Swiss	abnormal calcium ion homeostasis	J:111247
	abnormal cardiac muscle relaxation	J:111247
	abnormal locomotor activation	J:111247
	aorta coarctation	J:111247
	ascending aorta hypoplasia	J:111247
	atrial septal defect	J:111247
	bradykinesia	J:111247
	cardiac fibrosis	J:111247
	cardiac hypertrophy	J:111247
	cardiac interstitial fibrosis	J:111247
	decreased body weight	J:111247
	decreased cardiac muscle contractility	J:111247
	decreased litter size	J:111247
	dilated heart right ventricle	J:111247
	fatigue	J:111247
	globular heart	J:111247
	heart left ventricle hypertrophy	J:111247
	impaired righting response	J:111247
	increased heart left ventricle posterior wall thickness	J:111247
	increased heart left ventricle septal wall thickness	J:111247
	increased heart weight	J:111247
	neonatal lethality, incomplete penetrance	J:111247
	prenatal lethality, incomplete penetrance	J:111247
	thin ventricle myocardium compact layer	J:111247
	ventricular septal defect	J:111247
Atp2a2tm1Ges/Atp2a2+ involves: 129X1/SvJ	abnormal osteoclast differentiation	J:198051
Atp2a2tm1Ges/Atp2a2+ involves: 129X1/SvJ * Black Swiss	abnormal calcium ion homeostasis	J:52186, J:66006
	abnormal cardiac muscle relaxation	J:52186, J:95608
	cachexia	J:69754
	cardiac fibrosis	J:69754, J:95608
	cardiac hypertrophy	J:95608
	congestive heart failure	J:95608
	decreased left ventricle systolic pressure	J:52186
	decreased systemic arterial blood pressure	J:52186
	decreased ventricle muscle contractility	J:52186, J:66006, J:95608
	dilated heart left ventricle	J:95608
	esophageal epithelium hyperplasia	J:69754
	heart left ventricle hypertrophy	J:95608
	hyperkeratosis	J:69754
	increased esophageal papilloma incidence	J:69754
	increased heart left ventricle posterior wall thickness	J:95608
	increased left ventricle diastolic pressure	J:95608
	increased response of heart to induced stress	J:95608
	increased skin papilloma incidence	J:69754
	increased squamous cell carcinoma incidence	J:69754
	increased susceptibility to induced morbidity/mortality	J:95608
	increased tongue papilloma incidence	J:69754
	increased tumor incidence	J:69754
	lethargy	J:69754
	penis prolapse	J:69754
	premature death	J:69754
	pulmonary edema	J:95608
	stomach epithelial hyperplasia	J:69754
	toenail hyperkeratosis	J:69754
Atp2a2tm1Ges/Atp2a2tm1Ges involves: 129X1/SvJ * Black Swiss	prenatal lethality, complete penetrance	J:52186