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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
MGI:88106
37 phenotypes from 6 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Atp1a2tm1.1Tmklh/Atp1a2+
B6.129S1(Cg)-Atp1a2tm1.1Tmklh
abnormal emotion/affect behavior J:259556
abnormal impulsive behavior control J:259556
abnormal nervous system electrophysiology J:259556
abnormal social investigation J:259556
anhedonia J:259556
behavioral despair J:259556
excessive vocalization J:259556
hypoactivity J:259556
impaired coordination J:259556
increased body weight J:259556
increased glutamic acid level J:259556
increased grooming behavior J:259556
increased startle reflex J:259556
Atp1a2tm1.1Tmklh/Atp1a2tm1.1Tmklh
involves: 129S1/Sv * C57BL/6J
abnormal hippocampus physiology J:259556
neonatal lethality, complete penetrance J:259556
Atp1a2tm1Kwk/Atp1a2+
involves: 129X1/SvJ * C57BL/6J
abnormal fear/anxiety-related behavior J:83884
Atp1a2tm1Kwk/Atp1a2tm1Kwk
involves: 129X1/SvJ * C57BL/6J
abnormal amygdala morphology J:83884
abnormal olfactory cortex morphology J:83884
normal embryo phenotype J:83884
neonatal lethality, complete penetrance J:83884
Atp1a2tm2Kwk/Atp1a2+
B6.129X1-Atp1a2tm2Kwk
no abnormal phenotype detected J:94810
Atp1a2tm2Kwk/Atp1a2tm2Kwk
B6.129X1-Atp1a2tm2Kwk
abnormal action potential J:94810
abnormal nervous system electrophysiology J:94810
abnormal neurotransmitter level J:94810
abnormal somatic nervous system physiology J:94810
increased gamma-aminobutyric acid level J:94810
neonatal lethality, complete penetrance J:94810
no spontaneous movement J:94810
respiratory failure J:94810
unresponsive to tactile stimuli J:94810
Atp1a2tm2Ling/Atp1a2+
involves: 129P2/OlaHsd
abnormal muscle contractility J:114415
Atp1a2tm2Ling/Atp1a2+
involves: 129P2/OlaHsd * Black Swiss
abnormal spatial learning J:117414
normal homeostasis/metabolism phenotype J:117414
increased anxiety-related response J:117414
Atp1a2tm2Ling/Atp1a2+
involves: 129P2/OlaHsd * C57BL/6 * Black Swiss
decreased cardiac muscle contractility J:55191
Atp1a2tm2Ling/Atp1a2tm2Ling
involves: 129P2/OlaHsd * C57BL/6 * Black Swiss
neonatal lethality, complete penetrance J:55191
Atp1a2tm3Ling/Atp1a2tm3Ling
involves: 129S6/SvEvTac * Black Swiss
abnormal cardiac muscle contractility J:87082
normal cardiovascular system phenotype J:87082
Atp1a2tm4.1Ling/Atp1a2tm4.1Ling
Tg(Tagln-cre)1Her/0
involves: Black Swiss * C57BL/6 * SJL
abnormal systemic arterial blood pressure J:177051
cardiac hypertrophy J:177051
normal cardiovascular system phenotype J:177051
increased heart weight J:177051

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory