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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ank2
ankyrin 2, brain
MGI:88025
41 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Ank2tm1Bnt/Ank2+
involves: 129
abnormal fat cell differentiation J:222913
abnormal physiological response to xenobiotic J:163867
abnormal sinoatrial node conduction J:163867
decreased adipocyte glucose uptake J:222913
increased heart rate variability J:163867
Ank2tm1Bnt/Ank2tm1Bnt
involves: 129
normal nervous system phenotype J:186168
Ank2tm1Bnt/Ank2tm1Bnt
involves: 129X1/SvJ * C57BL/6
abnormal anterior corticospinal tract morphology J:52124
abnormal axon morphology J:52124
abnormal lateral corticospinal tract morphology J:52124
abnormal locomotor behavior J:52124
decreased body weight J:52124
decreased brain internal capsule size J:52124
decreased corpus callosum size J:52124
disorganized secondary lens fibers J:52124, J:70385
enlarged lateral ventricles J:52124
impaired balance J:52124
neonatal lethality, incomplete penetrance J:52124
optic nerve degeneration J:52124
postnatal lethality, complete penetrance J:52124
Ank2tm2.1Bnt/Ank2+
STOCK Ank2tm2Bnt/J
impaired glucose tolerance J:222913
premature death J:222913
Ank2tm2.1Bnt/Ank2tm2.1Bnt
STOCK Ank2tm2Bnt/J
abnormal fat cell differentiation J:222913
abnormal gluconeogenesis J:222913
normal behavior/neurological phenotype J:222913
hepatic steatosis J:222913
normal homeostasis/metabolism phenotype J:222913
impaired glucose tolerance J:222913
increased adipocyte glucose uptake J:222913
increased body weight J:222913
increased circulating free fatty acid level J:222913
increased circulating glucose level J:222913
increased epididymal fat pad weight J:222913
increased fat cell size J:222913
increased susceptibility to age related obesity J:222913
increased susceptibility to diet-induced obesity J:222913
insulin resistance J:222913
normal muscle phenotype J:222913
Ank2tm3.1Bnt/Ank2+
B6.129(C)-Ank2tm3.1Bnt/J
impaired glucose tolerance J:222913
increased circulating glucose level J:222913
increased susceptibility to age related obesity J:222913
premature death J:222913
Ank2tm3.1Bnt/Ank2tm3.1Bnt
B6.129(C)-Ank2tm3.1Bnt/J
abnormal fat cell differentiation J:222913
abnormal gluconeogenesis J:222913
abnormal glucose homeostasis J:222913
normal behavior/neurological phenotype J:222913
decreased adipocyte glucose uptake J:222913
decreased circulating insulin level J:222913
decreased insulin secretion J:222913
decreased muscle cell glucose uptake J:222913
hepatic steatosis J:222913
normal homeostasis/metabolism phenotype J:222913
impaired glucose tolerance J:222913
increased adipocyte glucose uptake J:222913
increased body weight J:222913
increased circulating free fatty acid level J:222913
increased circulating glucose level J:222913
increased epididymal fat pad weight J:222913
increased fat cell size J:222913
increased muscle cell glucose uptake J:222913
increased susceptibility to age related obesity J:222913
increased susceptibility to diet-induced obesity J:222913
increased total body fat amount J:222913
insulin resistance J:222913

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory