80 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Albem12Mvw/Albem12Mvw Fcgrttm1Dcr/Fcgrttm1Dcr Tg(FCGRT)32Dcr/Tg(FCGRT)32Dcr B6.Cg-Tg(FCGRT)32Dcr Albem12Mvw Fcgrttm1Dcr/MvwJ	decreased circulating serum albumin level	J:101977
Albtm1(cre/ERT2)Mtz/Alb+ Krastm4Tyj/Kras+ Ptentm2Mak/Ptentm2Mak involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae	increased cholangiocarcinoma incidence	J:254370
	increased hepatocellular carcinoma incidence	J:254370
Albtm1(cre/ERT2)Mtz/Alb+ Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6	increased cholangiocarcinoma incidence	J:192740
Albtm1(cre/ERT2)Mtz/Alb+ Per2tm1Jt/Per2+ Smg6tm1.1Tac/Smg6tm1.1Tac involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J	abnormal circadian behavior phase	J:342742
	abnormal circardian behavior entrainment	J:342742
	abnormal locomotor circadian rhythm	J:342742
	prolonged circadian behavior period	J:342742
Albtm1(cre/ERT2)Mtz/Alb+ Nr5a2tm1Sjns/Nr5a2tm1Sjns involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL	abnormal bile salt level	J:129068
	abnormal feces composition	J:129068
	abnormal intestinal lipid absorption	J:129068
	increased bile salt level	J:129068
Albtm1(cre/ERT2)Mtz/Alb+ Hes1tm1Kag/Hes1tm1Kag involves: 129S2/SvPas * C57BL/6 * CBA	normal neoplasm	J:192740
Albtm1(cre/ERT2)Mtz/Alb+ Fth1tm1.1Lck/Fth1tm1.1Lck involves: 129/Sv * C57BL/6 * SJL	abnormal liver iron level	J:166515
	normal liver/biliary system phenotype	J:166515
Albtm1(cre/ERT2)Mtz/Alb+ Hcfc1tm1Lwh/Hcfc1+ involves: 129S2/SvPas * C57BL/6	impaired liver regeneration	J:231596
Albtm1(cre/ERT2)Mtz/Alb+ Polr2mtm1.1Rgr/Polr2mtm1.1Rgr Trp53tm1Tyj/Trp53tm1Tyj involves: 129S2/SvPas * C57BL/6	increased hepatocyte karyomegaly	J:291184
	increased hepatocyte proliferation	J:291184
Albtm1(cre/ERT2)Mtz/Albtm1(cre/ERT2)Mtz Slc2a2tm2Thor/Slc2a2tm2Thor involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal bile salt level	J:197607
	abnormal circulating glucose level	J:197607
	abnormal glucose homeostasis	J:197607
	abnormal glycogen homeostasis	J:197607
	abnormal lipid homeostasis	J:197607
	decreased cellular glucose uptake	J:197607
	decreased insulin secretion	J:197607
	decreased liver cholesterol level	J:197607
	decreased liver triglyceride level	J:197607
	normal homeostasis/metabolism phenotype	J:197607
	impaired glucose tolerance	J:197607
	increased liver glycogen level	J:197607
	increased muscle cell glucose uptake	J:197607
G6pc1tm1.1Ics/G6pc1tm1.1Ics Albtm1(cre/ERT2)Mtz/Alb+ involves: 129S2/SvPas * C57BL/6J	abnormal blood homeostasis	J:195257
	abnormal hepatocyte morphology	J:195257
	enlarged liver	J:195257
	hepatic steatosis	J:195257
	normal homeostasis/metabolism phenotype	J:195257
	increased blood uric acid level	J:195257
	increased circulating cholesterol level	J:195257
	increased circulating triglyceride level	J:195257
	increased liver adenoma incidence	J:195257
	increased liver glycogen level	J:195257
	increased liver triglyceride level	J:195257
	increased liver weight	J:195257
	pale liver	J:195257
Gt(ROSA)26Sortm2(OVA/EGFP)Dwir/Gt(ROSA)26Sor+ Albtm1(cre/ERT2)Mtz/Alb+ involves: 129P2/OlaHsd * 129S2/SvPas	abnormal hepatocyte physiology	J:173806
Gt(ROSA)26Sortm2(OVA/EGFP)Dwir/Gt(ROSA)26Sor+ Tg(TcraTcrb)1100Mjb/0 Albtm1(cre/ERT2)Mtz/Alb+ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	increased circulating alanine transaminase level	J:173806
Mir32em1Gpt/Mir32em1Gpt Albem1(icre)Gpt/Alb+ C57BL/6JGpt-Mir32em1Gpt Albem1(icre)Gpt	abnormal lipid metabolism	J:344660
	abnormal liver physiology	J:344660
	normal behavior/neurological phenotype	J:344660
	decreased circulating alanine transaminase level	J:344660
	decreased circulating aspartate transaminase level	J:344660
	decreased circulating cholesterol level	J:344660
	decreased circulating LDL cholesterol level	J:344660
	decreased endoplasmic reticulum stress	J:344660
	decreased liver cholesterol level	J:344660
	decreased liver triglyceride level	J:344660
	decreased liver weight	J:344660
	decreased susceptibility to diet-induced hepatic steatosis	J:344660
	normal growth/size/body region phenotype	J:344660
	normal homeostasis/metabolism phenotype	J:344660
	improved glucose tolerance	J:344660
	increased insulin sensitivity	J:344660
Mob1atm1.1Asuz/Mob1atm1.1Asuz Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Albtm1(cre/ERT2)Mtz/Alb+ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	increased hepatobiliary system tumor incidence	J:228499
Orc1tm1.1Gle/Orc1tm1.1Gle Albtm1(cre/ERT2)Mtz/Alb+ involves: 129S2/SvPas * C57BL/6 * SJL	normal cellular phenotype	J:272584
	decreased hepatocyte number	J:272584
	increased hepatocyte karyomegaly	J:272584
	normal liver/biliary system phenotype	J:272584
	polyploidy	J:272584
Slc2a9tm1.1Thor/Slc2a9+ Albtm1(cre/ERT2)Mtz/Alb+ involves: 129S2/SvPas * C57BL/6 * C57BL/6N	increased urine magnesium level	J:153089
	increased urine phosphate level	J:153089
Slc2a9tm1.1Thor/Slc2a9tm1.1Thor Albtm1(cre/ERT2)Mtz/Alb+ involves: 129S2/SvPas * C57BL/6 * C57BL/6N	decreased urine osmolality	J:153089
	decreased urine pH	J:153089
	increased blood uric acid level	J:153089
	increased urine magnesium level	J:153089
	increased urine phosphate level	J:153089
	increased urine potassium level	J:153089
	polyuria	J:153089
	normal renal/urinary system phenotype	J:153089
	uraturia	J:153089
Uri1tm1.1Ndj/Uri1+ Albtm1(cre/ERT2)Mtz/Alb+ B6.Cg-Albtm1(cre/ERT2)Mtz Uri1tm1.1Ndj	abnormal enzyme/coenzyme level	J:217463
	decreased incidence of tumors by chemical induction	J:217463
	decreased susceptibility to injury	J:217463
Uri1tm1.1Ndj/Uri1tm1.1Ndj Albtm1(cre/ERT2)Mtz/Alb+ B6.Cg-Albtm1(cre/ERT2)Mtz Uri1tm1.1Ndj	abnormal liver morphology	J:217463
	hepatic necrosis	J:217463
	increased circulating alanine transaminase level	J:217463
	increased hepatocyte apoptosis	J:217463
	liver failure	J:217463
	liver hemorrhage	J:217463
	liver inflammation	J:217463
	postnatal lethality	J:217463
Ywhabem1Gpt/Ywhabem1Gpt Albem1(icre)Gpt/Alb+ C57BL/6JGpt-Ywhabem1Gpt Albem1(icre)Gpt	decreased liver glycogen level	J:323777
	enhanced gluconeogenesis	J:323777
	impaired glucose tolerance	J:323777
	increased circulating glucose level	J:323777