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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Acta1
actin alpha 1, skeletal muscle
MGI:87902
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Acta1tm1Hrd/Acta1+
Tg(Myl1-Igf1)1Nros/?
either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6JArc * FVB/N)
abnormal muscle fiber morphology J:184588
abnormal muscle weight J:184588
normal behavior/neurological phenotype J:184588
increased grip strength J:184588
premature death J:184588
Acta1tm1Hrd/Acta1+
Tg(MSV-SKI)33Hugh/?
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6JArc)
abnormal grip strength J:184588
abnormal muscle fiber morphology J:184588
abnormal muscle weight J:184588
normal behavior/neurological phenotype J:184588
decreased locomotor activity J:184588
premature death J:184588
Acta1tm1Hrd/Acta1+
Tg(ACTA1-FHL1)#Cmit/?
either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6JArc * FVB/N)
abnormal muscle fiber morphology J:184588
abnormal muscle weight J:184588
normal behavior/neurological phenotype J:184588
increased grip strength J:184588
premature death J:184588
Acta1tm1Jll/Acta1+
Tg(ACTA1*D286G)#Kjno/Tg(ACTA1*D286G)#Kjno
involves: C57BL/6 * CBA
abnormal muscle fiber morphology J:209273
abnormal skeletal muscle morphology J:209273
abnormal Z line morphology J:209273
decreased body weight J:209273
hindlimb paralysis J:209273
increased variability of skeletal muscle fiber size J:209273
premature death J:209273
reduced fertility J:209273

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory