Acta1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acta1
actin alpha 1, skeletal muscle
MGI:87902

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acta1^tm1Hrd/Acta1⁺ either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6JArc)	abnormal muscle fiber morphology	J:184588
	abnormal sarcomere morphology	J:184588
	blepharoptosis	J:184588
	decreased body weight	J:184588
	decreased grip strength	J:184588
	decreased locomotor activity	J:184588
	decreased muscle weight	J:184588
	excessive tearing	J:184588
	facial muscle atrophy	J:184588
	premature death	J:184588
Acta1^tm1Jll/Acta1^tm1Jll involves: 129P2/OlaHsd * Black Swiss	abnormal muscle development	J:78070
	abnormal muscle physiology	J:78070
	abnormal skeletal muscle fiber morphology	J:78070
	decreased body size	J:78070
	decreased body weight	J:78070
	decreased brown adipose tissue amount	J:78070
	decreased glycogen level	J:78070
	decreased liver glycogen level	J:78070
	decreased skeletal muscle fiber diameter	J:78070
	decreased skeletal muscle glycogen level	J:78070
	muscle weakness	J:78070
	postnatal lethality, complete penetrance	J:78070
	scoliosis	J:78070

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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