Mfsd2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mfsd2b
MFSD2 lysolipid transporter B, sphingolipid
MGI:3583946

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mfsd2b^{tm1a(KOMP)Wtsi}/Mfsd2b^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Mfsd2b^{tm1a(KOMP)Wtsi}/Wtsi	decreased circulating iron level	J:175295
	decreased erythrocyte cell number	J:175295
	increased mean corpuscular hemoglobin	J:175295
Mfsd2b^{tm1a(KOMP)Wtsi}/Mfsd2b^{tm1a(KOMP)Wtsi} C57BL/6-Mfsd2b^{tm1a(KOMP)Wtsi}	abnormal ceramide level	J:250123
	abnormal mean corpuscular volume	J:250123
	abnormal stress erythropoiesis	J:250123
	decreased B cell number	J:250123
	decreased erythrocyte cell number	J:250123
	decreased leukocyte cell number	J:250123
	decreased sphingosine level	J:250123
	decreased T cell number	J:250123
	enlarged spleen	J:250123
	normal hematopoietic system phenotype	J:250123
	hemolysis	J:250123
	normal homeostasis/metabolism phenotype	J:250123
	increased sphingosine level	J:250123
	increased susceptibility to type I hypersensitivity reaction	J:250123
	reticulocytopenia	J:250123
	stomatocytosis	J:250123

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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