Trpa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trpa1
transient receptor potential cation channel, subfamily A, member 1
MGI:3522699

20 phenotypes from 8 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trpa1^em1(IMPC)J/Trpa1^em1(IMPC)J C57BL/6NJ-Trpa1^em1(IMPC)J/Mmjax	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
Trpa1^m1Btlr/Trpa1^m1Btlr C57BL/6J-Trpa1^m1Btlr	decreased fear-related response	J:262266
Trpa1^m2Btlr/Trpa1^m2Btlr C57BL/6J-Trpa1^m2Btlr	decreased fear-related response	J:265161
Trpa1^tm1.1Bju/Trpa1^tm1.1Bju involves: C57BL/6J	abnormal bronchial provocation	J:160860
	abnormal neuron physiology	J:160860, J:161343
	abnormal sensory neuron physiology	J:161343
	decreased physiological sensitivity to xenobiotic	J:160860
Trpa1^tm1Jul/Trpa1⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal acute inflammation	J:115886
	abnormal mechanical nociception	J:115886
	abnormal nervous system physiology	J:115886
	abnormal thermal nociception	J:115886
	hyperalgesia	J:115886
	increased chemical nociceptive threshold	J:115886
Trpa1^tm1Jul/Trpa1^tm1Jul involves: 129P2/OlaHsd * C57BL/6	abnormal nervous system physiology	J:115886
Trpa1^tm1Kykw/Trpa1^tm1Kykw involves: 129P2/OlaHsd * C57BL/6J	abnormal taste sensitivity	J:108343
	abnormal thermosensation	J:108343
	decreased threshold for auditory brainstem response	J:108343
	hyporesponsive to tactile stimuli	J:108343
	increased thermal nociceptive threshold	J:108343
Trpa1^tm2.1Kykw/Trpa1^tm2.1Kykw involves: 129S6/SvEvTac	hypoalgesia	J:169738
Trpa1^tm2Kykw/Trpa1^tm2Kykw involves: 129S6/SvEvTac	no abnormal phenotype detected	J:169738

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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