Ticam2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ticam2
TIR domain containing adaptor molecule 2
MGI:3040056

6 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ticam2^M1Btlr/Ticam2⁺ C57BL/6J-Ticam2^M1Btlr	decreased tumor necrosis factor secretion	J:215010
Ticam2^M1Btlr/Ticam2^M1Btlr C57BL/6J-Ticam2^M1Btlr	decreased tumor necrosis factor secretion	J:215010
Ticam2^M2Btlr/Ticam2⁺ C57BL/6J-Ticam2^M2Btlr	decreased interleukin-1 beta secretion	J:254908
Ticam2^M2Btlr/Ticam2^M2Btlr C57BL/6J-Ticam2^M2Btlr	decreased interleukin-1 beta secretion	J:254908
Ticam2^M3Btlr/Ticam2⁺ C57BL/6J-Ticam2^M3Btlr	decreased tumor necrosis factor secretion	J:254912
Ticam2^M3Btlr/Ticam2^M3Btlr C57BL/6J-Ticam2^M3Btlr	decreased tumor necrosis factor secretion	J:254912
Ticam2^tm1Aki/Ticam2^tm1Aki involves: C57BL/6	abnormal immune system physiology	J:86256
	decreased interleukin-6 secretion	J:86256
	increased susceptibility to Coronaviridae infection	J:270045
Ticam2^tm1Btlr/Ticam2^tm1Btlr C57BL/6J-Ticam2^tm1Btlr	abnormal interferon secretion	J:133619
Ticam2^tm1Btlr/Ticam2^tm1Btlr C57BL/6J-Ticam2^tm1Btlr	decreased tumor necrosis factor secretion	J:133619

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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