Med13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Med13
mediator complex subunit 13
MGI:3029632

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Med13^tm1Eno/Med13^tm1Eno Tg(Myh6-cre)2182Mds/0 involves: 129 * C57BL/6 * FVB/N	normal cardiovascular system phenotype	J:186193
	impaired glucose tolerance	J:186193
	increased abdominal adipose tissue amount	J:186193
	increased body weight	J:186193
	increased brown adipose tissue amount	J:186193
	increased circulating cholesterol level	J:186193
	increased circulating insulin level	J:186193
	increased circulating leptin level	J:186193
	increased circulating triglyceride level	J:186193
	increased lean body mass	J:186193
	increased liver triglyceride level	J:186193
	increased liver weight	J:186193
	increased susceptibility to diet-induced obesity	J:186193
	increased total body fat amount	J:186193
	increased white fat cell size	J:186193
Tg(Myh6-Med13)1Eno/0 B6.Cg-Tg(Myh6-Med13)1Eno	abnormal circulating cholesterol level	J:186193
	abnormal interscapular fat pad morphology	J:186193
	abnormal liver triglyceride level	J:186193
	decreased body weight	J:186193
	decreased interscapular fat pad weight	J:186193
	decreased susceptibility to diet-induced obesity	J:186193
	decreased total body fat amount	J:186193
	decreased white adipose tissue amount	J:186193
	normal homeostasis/metabolism phenotype	J:186193
	improved glucose tolerance	J:186193
	increased carbon dioxide production	J:186193
	increased oxygen consumption	J:186193

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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