Sprtn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sprtn
SprT-like N-terminal domain
MGI:2685351

23 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ Sprtn^tm1.1Yjm/Sprtn^tm1.1Yjm involves: 129S/SvEv * 129S4/SvJae	chromosomal instability	J:297179
Sprtn^tm1.2Yjm/Sprtn^tm1.2Yjm involves: 129S/SvEv * C57BL/6	absent blastocoele	J:225198
	decreased inner cell mass proliferation	J:225198
	embryonic lethality, complete penetrance	J:225198
Sprtn^tm1Yjm/Sprtn^tm1.2Yjm involves: 129S/SvEv * C57BL/6	abnormal cell nucleus morphology	J:225198
	chromosomal instability	J:225198
	decreased fibroblast proliferation	J:225198
	preweaning lethality, complete penetrance	J:225198
Sprtn^tm1Yjm/Sprtn^tm1Yjm involves: 129S/SvEv * C57BL/6	cachexia	J:225198
	cataract	J:225198
	chromosomal instability	J:225198
	decreased body size	J:225198
	decreased gonadal fat pad weight	J:225198
	decreased inguinal fat pad weight	J:225198
	decreased interscapular fat pad weight	J:225198
	decreased renal fat pad weight	J:225198
	decreased total fat pad weight	J:225198
	decreased white fat cell size	J:225198
	early cellular replicative senescence	J:225198
	impaired exercise endurance	J:225198
	kyphosis	J:225198
	lordosis	J:225198
	normal muscle phenotype	J:225198
	premature aging	J:225198
	normal skeleton phenotype	J:225198

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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