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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Akap5
A kinase (PRKA) anchor protein 5
MGI:2685104
20 phenotypes from 5 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Akap5tm1.1Jsco/Akap5tm1.1Jsco
involves: 129S * C57BL/6
abnormal pancreatic beta cell morphology J:190017
decreased circulating insulin level J:190017
decreased insulin secretion J:190017
improved glucose tolerance J:190017
increased insulin sensitivity J:190017
Akap5tm1.1Jsco/Akap5tm1.1Jsco
involves: 129S * C57BL/6 * FVB/N
abnormal AMPA-mediated synaptic currents J:138972
abnormal spatial learning J:138972
decreased anxiety-related response J:138972
decreased susceptibility to pharmacologically induced seizures J:138972
impaired coordination J:138972
reduced long term depression J:138972
Akap5tm1Gsm/Akap5tm1Gsm
B6.129-Akap5tm1Gsm
reduced long term potentiation J:127739
Akap5tm1Gsm/Akap5tm1Gsm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
decreased circulating insulin level J:190017
normal homeostasis/metabolism phenotype J:190017
Akap5tm1Jsco/Akap5tm1Jsco
Tg(Ins2-cre)25Mgn/0
involves: 129S * C57BL/6 * DBA
decreased circulating insulin level J:190017
impaired glucose tolerance J:190017
increased insulin secretion J:190017
Akap5tm2Jsco/Akap5tm2Jsco
involves: 129 * C57BL/6
abnormal AMPA-mediated synaptic currents J:191219
abnormal excitatory postsynaptic potential J:191219
abnormal synaptic plasticity J:191219
absent long term depression J:191219
enhanced long term potentiation J:191219
normal nervous system phenotype J:191219
reduced long term depression J:191219
Akap5tm2Jsco/Akap5tm2Jsco
involves: 129 * C57BL/6 * C57BL/6J
decreased circulating insulin level J:190017
decreased insulin secretion J:190017
improved glucose tolerance J:190017
increased insulin sensitivity J:190017
Akap5tm3Jsco/Akap5tm3Jsco
involves: 129 * C57BL/6
abnormal synaptic plasticity J:211790

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory