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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dhps
deoxyhypusine synthase
MGI:2683592
15 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
DhpsGt(RRM039)Byg/DhpsGt(RRM039)Byg
involves: 129P2/OlaHsd * C57BL/6J 		abnormal preimplantation embryo development J:285882
decreased cell proliferation J:285882
embryonic lethality between implantation and somite formation, complete penetrance J:285882
Dhpstm1Itl/Dhps+
involves: 129S/SvEv * C57BL/6 		no abnormal phenotype detected J:232390
Dhpstm1Itl/Dhpstm1Itl
involves: 129S/SvEv * C57BL/6 		embryonic lethality, complete penetrance J:232390
Dhpstm2a(EUCOMM)Wtsi/Dhps+
C57BL/6N-Dhpstm2a(EUCOMM)Wtsi/Wtsi 		increased hemoglobin content J:211773
Dhpstm2a(EUCOMM)Wtsi/Dhpstm2a(EUCOMM)Wtsi
C57BL/6N-Dhpstm2a(EUCOMM)Wtsi/Wtsi 		preweaning lethality, complete penetrance J:211773
Dhpstm2c(EUCOMM)Wtsi/Dhpstm2c(EUCOMM)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0
involves: C57BL/6J * C57BL/6N * CBA * SJL 		cachexia J:236582
decreased body weight J:236582
decreased bone marrow cell number J:236582
decreased spleen red pulp amount J:236582
increased kidney iron level J:236582
premature death J:236582
spleen hypoplasia J:236582
Dhpstm2d(EUCOMM)Wtsi/Dhpstm2d(EUCOMM)Wtsi
involves: BALB/cJ * C57BL/6J * C57BL/6N * SJL 		prenatal lethality, complete penetrance J:236582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory