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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Elane
elastase, neutrophil expressed
MGI:2679229
14 phenotypes from 4 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
ElaneM1Btlr/ElaneM1Btlr
C57BL/6J-ElaneM1Btlr 		decreased tumor necrosis factor secretion J:218967
Elanetm1(cre)Roes/Elanetm1(cre)Roes
involves: 129 		decreased susceptibility to bacterial infection induced morbidity/mortality J:77597
increased susceptibility to infection induced morbidity/mortality J:77597
Elanetm1(cre)Roes/Elanetm1(cre)Roes
involves: 129S6/SvEvTac 		impaired neutrophil recruitment J:137674
Elanetm1Link/Elanetm1Link
involves: 129X1/SvJ * C57BL/6 		normal hematopoietic system phenotype J:131496
normal immune system phenotype J:131496
no abnormal phenotype detected J:131496
Elanetm1Sds/Elanetm1Sds
129X1/SvJ-Elanetm1Sds 		abnormal neutrophil physiology J:47420
decreased susceptibility to bacterial infection induced morbidity/mortality J:47420
increased susceptibility to bacterial infection J:47420
increased susceptibility to bacterial infection induced morbidity/mortality J:47420
Elanetm1Sds/Elanetm1Sds
B6.129X1-Elanetm1Sds 		decreased physiological sensitivity to xenobiotic J:86599
Elanetm1Sds/Elanetm1Sds
B6.129X1-Elanetm1Sds/J 		abnormal pain threshold J:220590
abnormal response to injury J:220590
Elanetm1Sds/Elanetm1Sds
involves: 129X1/SvJ 		decreased physiological sensitivity to xenobiotic J:124377
Elanetm1Sds/Elanetm1Sds
involves: 129X1/SvJ * C57BL/6 		abnormal inflammatory response J:113463
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory