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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mir22
microRNA 22
MGI:2676896
27 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Col1a1tm1(CAG-Mir22)Ppp/Col1a1tm1(CAG-Mir22)Ppp
Tg(Mx1-cre)1Cgn/0
Not Specified
abnormal erythropoiesis J:199366
abnormal hematopoietic system morphology/development J:199366
anemia J:199366
decreased leukocyte cell number J:199366
enlarged spleen J:199366
increased hematopoietic stem cell number J:199366
increased leukemia incidence J:199366
increased myeloid dendritic cell number J:199366
increased T cell derived lymphoma incidence J:199366
Mir22tm1.1Arod/Mir22tm1.1Arod
involves: 129S1/SvImJ * 129S7/SvEvBrd
abnormal cardiovascular system physiology J:183005
cardiac fibrosis J:183005
normal cardiovascular system phenotype J:183005
congestive heart failure J:183005
decreased cardiac muscle contractility J:183005
dilated heart ventricle J:183005
increased physiological sensitivity to xenobiotic J:183005
Mir22tm1.2Dzw/Mir22tm1.2Dzw
involves: C57BL/6
normal cardiovascular system phenotype J:213308
decreased response of heart to induced stress J:213308
increased response of heart to induced stress J:213308
Mir22tm1Boet/Mir22tm1Boet
B6.129S2-Mir22tm1Boet
normal behavior/neurological phenotype J:266382
decreased body weight J:266382
decreased circulating free fatty acids level J:266382
decreased circulating leptin level J:266382
decreased white adipose tissue amount J:266382
decreased white fat cell size J:266382
normal homeostasis/metabolism phenotype J:266382
increased fatty acid oxidation J:266382
normal muscle phenotype J:266382

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory