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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Frem1
Fras1 related extracellular matrix protein 1
MGI:2670972
51 phenotypes from 7 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Frem1bat/Frem1+
C57BL/6J-Frem1bat
abnormal cranial suture morphology J:177282
asymmetric snout J:177282
premature metopic suture closure J:177282
short snout J:177282
trigonocephaly J:177282
Frem1bat/Frem1bat
C57BL/6J-Frem1bat
abnormal conjunctiva morphology J:200884
abnormal cornea morphology J:200884
abnormal craniofacial morphology J:177282
abnormal eye development J:92613
abnormal internasal suture morphology J:177282
abnormal kidney morphology J:92613
abnormal maxillary-premaxillary suture morphology J:177282
abnormal metopic suture morphology J:177282
abnormal midface morphology J:177282
abnormal nasal bone morphology J:177282
absent corneal epithelium J:200884
absent eyelids J:92613
bleb J:92613
broad nasal bone J:177282
coloboma J:200884
cryptophthalmos J:92613, J:200884
decreased cornea thickness J:200884
increased inner canthal distance J:200884
midface hypoplasia J:177282, J:200884
premature metopic suture closure J:177282
rectal prolapse J:200884
short philtrum J:200884
short snout J:177282, J:200884
single kidney J:92613
syndactyly J:92613
trigonocephaly J:177282
Frem1bfd/Frem1bfd
involves: C57BL/6J
abnormal digit morphology J:92613
abnormal eye morphology J:92613
abnormal kidney morphology J:92613
Frem1crf11/Frem1crf11
involves: C57BL/6J
abnormal craniofacial morphology J:85113
cryptophthalmos J:200175
fused right lung lobes J:200175
microphthalmia J:85113, J:200175
rectal prolapse J:200175
single kidney J:200175
Frem1eyes2/Frem1eyes2
C57BL/6J-Frem1eyes2
abnormal anogenital distance J:200175
abnormal eye morphology J:192553
abnormal postnatal growth/weight/body size J:89098
diaphragmatic hernia J:192553
eyelids fail to open J:89098
fused right lung lobes J:200175
single kidney J:192553
Frem1eyes2/Frem1eyes2
involves: 129S6/SvEvTac * C57BL/6J
abnormal diaphragm development J:192553
abnormal eye morphology J:192553
abnormal gallbladder morphology J:192553
cryptophthalmos J:192553
diaphragmatic hernia J:192553
fused right lung lobes J:200175
microphthalmia J:192553
preweaning lethality, incomplete penetrance J:192553
rectal prolapse J:192553
single kidney J:192553
Frem1heb/Frem1heb
involves: AKR/J
abnormal brain morphology J:6609
abnormal epidermal layer morphology J:6609
abnormal retina morphology J:6609
anophthalmia J:6609, J:64448
bleb J:64448
blistering J:6609
early eyelid opening J:64448
eyelids open at birth J:6609, J:64448
polydactyly J:6609, J:64448
prenatal lethality, incomplete penetrance J:64448
Frem1tm1Ksek/Frem1+
involves: 129 * C57BL/6
abnormal cranial suture morphology J:177282
Frem1tm1Ksek/Frem1tm1Ksek
involves: 129
abnormal kidney development J:185210
absent kidney J:185210
Frem1tm1Ksek/Frem1tm1Ksek
involves: 129 * C57BL/6
absent kidney J:111788
blistering J:111788
cryptophthalmos J:111788
premature metopic suture closure J:177282
syndactyly J:111788
Frem1tm2.1Ksek/Frem1tm2.1Ksek
involves: 129 * C57BL * C57BL/6 * DBA
no abnormal phenotype detected J:185210

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory