Socs7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Socs7
suppressor of cytokine signaling 7
MGI:2651588

27 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Socs7^M1Btlr/Socs7⁺ C57BL/6J-Socs7^M1Btlr	decreased body weight	J:234255
Socs7^M1Btlr/Socs7^M1Btlr C57BL/6J-Socs7^M1Btlr	decreased body weight	J:234255
Socs7^{tm1a(EUCOMM)Wtsi}/Socs7^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Socs7^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal behavior	J:175295
	abnormal eye size	J:175295
Socs7^{tm1a(EUCOMM)Wtsi}/Socs7^{tm1a(EUCOMM)Wtsi} involves: C57BL/6 * C57BL/6N	decreased response to stress-induced hyperthermia	J:213427
	persistent hyaloid artery	J:213427
	testis degeneration	J:213427
Socs7^{tm1c(EUCOMM)Wtsi}/Socs7^{tm1c(EUCOMM)Wtsi} Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6N * SJL	abnormal neocortex morphology	J:205551
	normal nervous system phenotype	J:205551
Socs7^tm1Pbro/Socs7^tm1Pbro B6.129S1-Socs7^tm1Pbro	hydrocephaly	J:100915
	hypoglycemia	J:100915
	postnatal growth retardation	J:100915
	postnatal lethality, complete penetrance	J:100915
Socs7^tm1Pbro/Socs7^tm1Pbro involves: 129S1/Sv * C57BL/6	abnormal glucose homeostasis	J:100915
	improved glucose tolerance	J:100915
	increased insulin sensitivity	J:100915
	normal mortality/aging	J:100915
Socs7^tm1Wsa/Socs7^tm1Wsa involves: C57BL/6	abnormal cerebral cortex morphology	J:93449
	abnormal cranial suture morphology	J:93449
	abnormal hippocampus morphology	J:93449
	abnormal subcommissural organ morphology	J:93449
	aphagia	J:93449
	decreased body weight	J:93449
	decreased locomotor activity	J:93449
	enlarged pancreatic islets	J:93449
	hydrocephaly	J:93449
	intracranial hemorrhage	J:93449
	lethargy	J:93449
	megacephaly	J:93449
	premature death	J:93449

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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